干蟾化学成分的研究Studies on Chemical Constituents of Bufo Siccus
陈玉俊,项进,顾维,许美娟
Chen Yujun,Xiang Jin,Gu Wei and Xu Meijuan (Jiangsu Provincial Institute of Materia Medica,Nanjing 210009)
摘要(Abstract):
目的:探讨干蟾的化学成分。方法:硅胶柱层析分离,薄层层析和光谱技术鉴定化合物的结构。结果:分离得到6个化合物,分别为胆甾醇、β谷甾醇、脂蟾毒配基、华蟾毒精、蟾毒灵、日蟾毒它灵。结论:首次报道了干蟾的化学成分
Objective:To study the chemical constituents of Bufo Siccus.Method:Based on silica column chromatography six compounds were obtained from the alcoholic extract of Bufo Siccus and identified by physico chemical and spectroscopic analyses.Result:The compounds were identified as cholesterol,β sitosterol,resibufogenin,cinobufagin,bufalin and gamabufotalin.Conclusion:Studies on the chemical constituents of Bufo Siccus were reported for the first time.
关键词(KeyWords):
干蟾,脂蟾毒配基,华蟾毒精,蟾毒灵,日蟾毒它灵
Bufo Siccus;resibufogenin;cinobufagin;bufalin;gamabufotalin
基金项目(Foundation):
作者(Author):
陈玉俊,项进,顾维,许美娟
Chen Yujun,Xiang Jin,Gu Wei and Xu Meijuan (Jiangsu Provincial Institute of Materia Medica,Nanjing 210009)