中国中药杂志

1998, (05) 3-5

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党参对犬的胃酸及血清胃泌素、血浆生长抑素的影响
The Effect of Codonopsis pilosula (Franch.)Nannf.on Gastric Acid,Serum Gastrin and Plasma Somatostatin Concentration in Dogs

陈少夫,周卓,孙素云,李宇权,李辛
Chen Shaofu,ZhouZhuo,Sun Suyun and Li Yuquan(Second Clinical College of China Medical University,Shenyang 110003)Li Xin (Shenyang Pharmaceutical University,Shenyang 110015)

摘要(Abstract):

对带有海氏小胃的犬,灌入党参后海氏小胃的胃排酸量较对照组无明显变化(P>0.05)。灌入党参10g后150min,灌入党参20g后90,150min以及灌入党参40g后30,60,150min,血清胃泌素浓度较对照组明显升高(P<0.05或P<0.01)。灌入党参后血浆生长抑素浓度无明显变化(P>0.05)。
The results were obtained by oral administration of the decoction of Codonopsis pilosula in three different doses(10g,20g,40g) to 5 dogs with Heidenhain pouch.No significant changes occurred in the acidity output of Heidenhain pouch and plasma somatostatin concentration out of the oral administration (P>0.05).A significant increase occurred in serum gastrin concentration (P<0.05 or P<0.01)150min after a dose of 10g,90min and 150min after doses of 20g,and 30min,60min,and 150min after doses of 40g.

关键词(KeyWords): 党参,胃酸,胃泌素,生长抑素
Codonopsis pilosula;gastric acid;gastrin;somatostatin

Abstract:

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基金项目(Foundation): 辽宁省科委博士起动基金

作者(Author): 陈少夫,周卓,孙素云,李宇权,李辛
Chen Shaofu,ZhouZhuo,Sun Suyun and Li Yuquan(Second Clinical College of China Medical University,Shenyang 110003)Li Xin (Shenyang Pharmaceutical University,Shenyang 110015)

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