大孔吸附树脂吸附纯化不同中药有效部位特性研究Application and Characteristics of Macroreticular Resin in Purification Study of Different Effective Ingredients in Chinese Medicines
朱浩,侯世祥,孙毅毅,毛声俊
Zhu Hao,Hou Shixiang,Sun Yiyi and Mao Shengjun (School of Pharmacy,West China University of Medical Sciences,Chengdu 610041)
摘要(Abstract):
目的:探讨LD605型号大孔吸附树脂纯化具不同母核结构有效部位的特性,并为含有复合有效部位的中药复方吸附纯化的深入研究和推广应用奠定基础。方法:以含生物碱、黄酮、水溶性酚性化合物和无机矿物质4种中药有效部位的单味药材(黄连、葛根、丹参、石膏)水提液为样本,在LD605型树脂上进行动态吸附研究,比较其吸附特性参数。结果:除无机矿物质外,其他中药有效部位均可不同程度地被树脂吸附纯化。结论:使用大孔吸附树脂纯化中药复方的设想基本可行,但应根据药材和处方的实际情况选用适宜的纯化条件。
Objective:To evaluate the possibility of applying macroreticular resin to the purification of different effective ingredients in Chinese medicines and study its working characteristics.Method:Four samples (water extracts of four single Chinese medicinal materials) containing alkaloids,anthraquinones,water soluble phenols and inorganic salts were employed.Result:LD605 resin is able to adsorb different effective ingredients except inorganic salts.Conclusion:Purification of Chinese compound prescriptions can be achieved by means of macroreticular resin.
关键词(KeyWords):
大孔吸附树脂,中药有效部位,纯化,吸附纯化特性
macroreticular resin;effective ingredients;purification;characteristics of adsorbing purification
基金项目(Foundation):
作者(Author):
朱浩,侯世祥,孙毅毅,毛声俊
Zhu Hao,Hou Shixiang,Sun Yiyi and Mao Shengjun (School of Pharmacy,West China University of Medical Sciences,Chengdu 610041)
- 大孔吸附树脂,中药有效部位,纯化,吸附纯化特性
macroreticular resin - effective ingredients
- purification
- characteristics of adsorbing purification
- 朱浩
- 侯世祥
- 孙毅毅
- 毛声俊
Zhu Hao - Hou Shixiang
- Sun Yiyi and Mao Shengjun (School of Pharmacy
- West China University of Medical Sciences
- Chengdu 610041)
- 朱浩
- 侯世祥
- 孙毅毅
- 毛声俊
Zhu Hao - Hou Shixiang
- Sun Yiyi and Mao Shengjun (School of Pharmacy
- West China University of Medical Sciences
- Chengdu 610041)