窦德强,任杰,陈颖,裴玉萍,陈英杰
DOU De-qiang, REN Jie, CHEN Ying, PEI Yu-ping, CHEN Ying-jie (Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, China)

• 1:沈阳药科大学天然药物化学教研室
• 2:沈阳药科大学天然药物化学教研室
• 3:沈阳药科大学天然药物化学教研室
• 4:沈阳药科大学天然药物化学教研室

摘要(Abstract)：

目的 :分离鉴定人参根的化学成分。方法 :大孔吸附树脂、硅胶柱色谱及HPLC方法分离 ,通过对其进行理化常数和光谱分析方法确定结构。结果 :自商品人参中分离得到 16个皂苷类成分 ,分别鉴定为三七皂苷 R2 (1) ,人参皂苷 Rg2 (2 ) ,2 0 (R) Rg2 (3) ,人参皂苷 Rg1(4) , Rf(5 ) , Re(6 ) , Rd(7) , Rc(8) , Rb1(9) , Rb2 (10 ) , Rb3 (11) , Ra3 (12 ) , Ra2 (13) , Ra1(14 ) ,三七参苷 R4(15 )和人参皂苷 Ro(16 )。结论 :化合物 1为首次自本种植物分离得到。
Ojective: To isolate and elucidate the constituents from the roots of Commercial Ginseng. Method: Column chromatography and HPLC were used to isolate chemical constituents. Physico-chemical characters and spectr-oscopic analysis were employed for structural identification. Result: Sixteen compounds were identified as: notoginsenoside-R_2 (1), ginsenoside-Rg_2 (2), 20(R)-Rg_2(3), ginsenoside-Rg_1(4), -Rf(5), -Re(6), -Rd(7), -Rc(8), -Rb_1(9), -Rb_2(10), -Rb_3(11), -Ra_3(12),-Ra_2(13), -Ra_1(14), notoginsenoside-R_4(15) and ginsenoside -Ro(16). Conclusion: Compound 1 was obtained from the plant for the first time.

关键词(KeyWords)： 人参;人参皂苷;三七皂苷-R2
Panax ginseng ; ginsenoside; notoginsenoside

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 窦德强,任杰,陈颖,裴玉萍,陈英杰
DOU De-qiang, REN Jie, CHEN Ying, PEI Yu-ping, CHEN Ying-jie (Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, China)

参考文献(References)：

• [1]　DouDQ ,HouWB ,ChenYJ .StudiesontheCharacteristicConstituentsofChineseginsengandAmericanginseng.PlantaMed,1998;64:555.
• [2]　DouDQ ,ChenYJ,LiangLH ,etal.SixNewDammarane typeTriterpeneSaponinsfromtheLeavesofPanaxginseng.ChemPharmBull,2001;49(4):442.
• [3]　窦德强.人参茎叶总皂甙的化学成分及减轻醋酸泼尼松副作用的研究.沈阳药科大学硕士研究生毕业论文.1995.6:14.
• [4]　ZhaoJ,WuM ,TaniyasuS .DammaraneSaponinsofSanchi gin seng,RootsofPanaxnotoginseng.ChemPharmBull,1981;29:2844.