中国中药杂志

2021, v.46(24) 6568-6573

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通塞脉片/胶囊治疗周围血管疾病临床应用专家共识
Expert consensus on Tongsaimai Tablets/Capsules in treatment of peripheral vascular diseases in clinical practice

曹烨民;王御震;裴晓华;杨博华;赵诚;方豫东;阙华发;姜玉峰;徐旭英;夏成勇;张建强;何春红;马立人;
CAO Ye-min;WANG Yu-zhen;PEI Xiao-hua;YANG Bo-hua;ZHAO Cheng;FANG Yu-dong;QUE Hua-fa;JIANG Yu-feng;XU Xu-ying;XIA Cheng-yong;ZHANG Jian-qiang;HE Chun-hong;MA Li-ren;Shanghai Integrated Traditional Chinese and Western Medicine Hospital Affiliated to Shanghai University of Traditional Chinese Medicine/Shanghai Institute of Integrated Traditional Chinese and Western Medicine and Vascular Diseases;Xiamen Hospital of Beijing University of Chinese Medicine;Dongzhimen Hospital, Beijing University of Chi

摘要(Abstract):

通塞脉片/胶囊由金银花、当归、牛膝、党参、石斛、黄芪、玄参、甘草共8味中药组成,具有活血祛瘀、益气养阴的功效,广泛应用于周围血管疾病的治疗,临床应用40余年,积累了丰富的研究数据和应用经验。相关研究证据均表明,该药在改善周围血管疾病临床症状方面具有良好的临床疗效和药物经济学效益,同时该药也被多个专家共识、指南、教材所推荐,是目前临床上使用较多的中成药之一。为进一步提高临床医生对该药的认识,更好地指导临床合理用药,由中华中医药学会组织相关领域专家,共同起草该专家共识。该共识在临床医生问卷调查和通塞脉片/胶囊研究文献系统回顾的基础上,依据PICO化的临床问题检索文献,采用GRADE系统,基于现有最佳证据,充分结合专家经验,通过名义组法形成推荐意见或共识建议。该共识明确了通塞脉片/胶囊治疗周围血管疾病的适应症、用法用量、疗程、用药时间、合并用药和注意事项等,并说明其临床应用的安全性,适用于全国各级医院的周围血管科(血管外科)、中医外科(普外科)、内分泌科等临床医师、药师。
Tongsaimai Tablets/Capsules are composed of Lonicerae Japonicae Flos, Angelicae Sinensis Radix, Achyranthis Bidentatae Radix, Codonopsis Radix, Dendrobii Caulis, Astragali Radix, Scrophulariae Radix, and Glycyrrhizae Radix et Rhizoma, and are effective in promoting blood circulation, removing blood stasis, supplementing Qi, and nourishing Yin. It is widely used in the treatment of peripheral vascular diseases. With 40 years of clinical application, it has accumulated substantial research data and application experience. Its good clinical efficacy and pharmacoeconomic benefits in improving the clinical symptoms of peripheral vascular diseases have been confirmed by relevant research. Meanwhile, this drug has also been recommended by many expert consensus, guidelines, and teaching materials, serving as one of the most commonly used Chinese patent medicines in clinical practice. To further improve the understanding of the drug among clinicians and properly guide its clinical medication, the China Association of Chinese Medicine took the lead and organized experts to jointly formulate this expert consensus. Based on the questionnaire survey of clinicians and the systematic review of research literature on Tongsaimai Tablets/Capsules with clinical problems in the PICO framework, the consensus, combined with expert experience, concludes recommendations or consensus suggestions by GRADE system with the optimal evidence available through the nominal group technique. This consensus defines the indications, usage, dosage, course of treatment, medication time, combined medication, and precautions of Tongsaimai Tablets/Capsules in the treatment of peripheral vascular diseases, and explains the safety of its clinical application. It is recommended for clinicians and pharmacists in the peripheral vascular department(vascular surgery), traditional Chinese medicine surgery(general surgery), and endocrinology department of hospitals at all levels in China.

关键词(KeyWords): 通塞脉片/胶囊;周围血管疾病;专家共识;GRADE
Tongsaimai Tablets/Capsules;peripheral vascular disease;expert consensus;GRADE

Abstract:

Keywords:

基金项目(Foundation): 上海市卫生健康委员会“十三五”临床重点专科(中医外科)项目;; 上海市科委科研计划项目(18401932900)

作者(Authors): 曹烨民;王御震;裴晓华;杨博华;赵诚;方豫东;阙华发;姜玉峰;徐旭英;夏成勇;张建强;何春红;马立人;
CAO Ye-min;WANG Yu-zhen;PEI Xiao-hua;YANG Bo-hua;ZHAO Cheng;FANG Yu-dong;QUE Hua-fa;JIANG Yu-feng;XU Xu-ying;XIA Cheng-yong;ZHANG Jian-qiang;HE Chun-hong;MA Li-ren;Shanghai Integrated Traditional Chinese and Western Medicine Hospital Affiliated to Shanghai University of Traditional Chinese Medicine/Shanghai Institute of Integrated Traditional Chinese and Western Medicine and Vascular Diseases;Xiamen Hospital of Beijing University of Chinese Medicine;Dongzhimen Hospital, Beijing University of Chi

DOI: 10.19540/j.cnki.cjcmm.20211009.501

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