中药资源化学研究与资源循环利用途径及目标任务Research on resources chemistry of Chinese medicinal materials and resources recycling utilization ways and goals and tasks
段金廒;宿树兰;郭盛;江曙;刘培;严辉;钱大玮;朱华旭;唐于平;吴启南;
DUAN Jin-ao;SU Shu-lan;GUO Sheng;JIANG Shu;LIU Pei;YAN Hui;QIAN Da-wei;ZHU Hua-xu;TANG Yu-ping;WU Qi-nan;Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization,and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine,Nanjing University of Chinese Medicine;
摘要(Abstract):
中药资源化学研究目的是促进中药及天然药物资源的有效生产、合理利用和产业的提质增效。中医药事业的发展有赖于中药资源的高效利用和可持续发展,有赖于药用生物资源可利用物质、潜在利用价值的发现技术和手段,有赖于中药资源类群中资源性化学成分的多途径、多层次、精细化利用和产业链的有效延伸,从而实现其循环利用的资源化学研究和资源产业健康发展的目的。该文基于中药资源化学的研究思路,将围绕5个方面对中药资源化学与中药资源循环利用途径及目标任务进行论述:立足于资源稀缺性原则,寻找发现或人工生产可替代性资源,保护珍稀濒危物种及自然资源;立足于资源多宜性原则,通过系统性和精细化开发利用,实现资源价值增值和价值补偿,提升资源利用效率;立足于资源节约和环境友好原则,减少资源消耗,促进循环利用,降低资源成本,提升资源利用效益;基于化害为利的资源化策略,研究揭示外来入侵生物资源的药用及多途径利用价值并加以有效利用,转化和丰富我国药物资源体系;基于化学成分结构修饰策略,发掘和提升中药资源性化学物质的利用价值和潜在利用价值。以期为提升中药资源利用效率,推进中药资源循环经济产业发展,从根本上转变中药农业和中药工业的经济增长方式提供参考和借鉴。
The objects of research on the resources chemistry of Chinese medicinal materials( RCCMM) are promotion of efficient production,rational utilization and improving quality of CMM and natural products. The development of TCM cause depends on the efficient utilization and sustainable development of CMM,hinges on the technologies and methods for using and discovering medicinal biological resources,stand or fall on the extension of industy chains,detailed utilizaion of resource chemical components by multi-way,multi-level. All of these may help to the recycling utilization and sound development of RCMM. In this article,five respects were discussed to the RCCMM researches and resources recycling utilization ways and goals and tasks. First,based on the principle of resource scarcity,discovering or replacing CMM resources,protecting the rare or endangered species or resources. Second,based on the multifunctionality of CMM,realizing the value-added and value compensation,and promoting the utilization efficiency through systermatic and detailed exploitation and utilization. Third,based on the resource conservation and environment-friendly,reducing raw material consumption,lowering cost,promoting recycling utilization and elevating utilization efficiency. Fourth,based on the stratege of turning harm into good,using the invasive alien biological resources by multi-ways and enriching the medicial resources. Fifth,based on the method of structure modification of chemical components,exploring and enhancing the utility value of resouces chemical substances.These data should provide references and attention for improving the utilization efficiency,promoting the development of recycling economy,and changing the mode of economic growth of agriculture and industry of CMM fundamentally.
关键词(KeyWords):
中药资源;中药资源化学;中药资源循环利用
Chinese medicinal material(CMM) resources;resources chemistry of Chinese medicinal materials(RCCMM);recycling utilization of CMM
基金项目(Foundation): 江苏高校中药资源产业化过程协同创新中心建设专项;; 国家科技支撑计划项目(2012BAI29B02);; 江苏省“333高层次人才工程”第一层次培养对象资助项目(2013);; 江苏高校中药学优势学科Ⅱ期建设工程(2014-ysxk)
作者(Authors):
段金廒;宿树兰;郭盛;江曙;刘培;严辉;钱大玮;朱华旭;唐于平;吴启南;
DUAN Jin-ao;SU Shu-lan;GUO Sheng;JIANG Shu;LIU Pei;YAN Hui;QIAN Da-wei;ZHU Hua-xu;TANG Yu-ping;WU Qi-nan;Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization,and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine,Nanjing University of Chinese Medicine;
参考文献(References):
- [1]周荣汉,段金廒.植物化学分类学[M].上海:上海科学技术出版社,2005.
- [2]段金廒,宿树兰,钱大玮,等.中药资源化学研究思路方法与进展[J].中国天然药物,2009,7(3):333.
- [3]段金廒,周荣汉.中药资源学[M].北京:中国中医药出版社,2013.
- [4]欧阳平凯,韦萍,姚忠.生物化工研究现状与发展趋势[J].化工进展,2003(1):1.
- [5]欧阳平凯.加强生物催化与生物转化技术在我国药物源头创新中的应用[J].中国天然药物,2007(3):161.
- [6]周启星.资源循环科学与工程概论[M].北京:化学工业出版社,2013.
- [7]任德权,周荣汉.中药材生产质量管理规范(GAP)实施指南[M].北京:中国农业出版社,2003:106.
- [8]郭立玮.中药分离原理与技术[M].北京:人民卫生出版社,2010.
- [9]李和平.现代精细化工生产工艺流程图解[M].北京:化学工业出版社,2014.
- [10]中国药典.一部[S].2010.
- [11]崔克明.杜仲研究的历史现状和展望[J].西北林学院学报,1994,9(4):51.
- [12]王雪根,徐虹,欧阳平凯.游离整体细胞生物转化反应行为[J].南京化工大学学报:自然科学版,1999(3):32.
- [13]卢定强,韦萍,欧阳平凯,等.生物催化与生物转化的研究进展[J].化工进展,2004(6):585.
- [14]段金廒.中药废弃物的资源化利用[M].北京:化学工业出版社,2013.
- [15]张伯礼.中医药事业发展与中药材资源[C].南京:2014中药及天然药物资源国际学术研讨会暨CSNR天然药物专业委员会第十一届学术年会,2014.
- [16]张文秀.资源经济学[M].成都:四川大学出版社,2001.
- [17]徐妙芳,唐志荣,陈集双.入侵有害植物资源化利用及相关问题[J].生态安全,2007(13):34.
- [18]闫小玲,寿海洋,马金双.中国外来入侵植物研究现状及存在问题[J].植物分类与资源学报,2012,34(3):287.
- [19]徐正浩,王一平.外来入侵植物成灾的机制及防除对策[J].生态学杂志,2004,23(3):124.
- [20]严辉,郭盛,段金廒,等.江苏地区外来入侵植物及其资源化利用现状与应对策略[J].中国现代中药,2014(12):1.
- [21]段金廒,宿树兰,郭盛,等.中药废弃物的转化增效资源化模式及其研究与实践[J].中国中药杂志,2013,38(23):3991.
- [22]纪明山.生物农药手册[M].北京:化学工业出版社,2011.
- [23]范如芹,罗佳,高岩,等.农业废弃物的基质化利用研究进展[J].江苏农业学报,2014,30(2):442.
- [24]刘清术,刘前刚,陈海荣,等.生物农药的研究动态、趋势及前景展望[J].农药研究与应用,2007,11(1):17.
- [25]李淑君.植物纤维水解技术[M].北京:化学工业出版社,2009.
- [26]马骁驰,果德安.中药活性成分生物转化的研究思路与方法[J].中国天然药物,2007(3):162.
- [27]贺赐安,余旭亚,孟庆雄,等.生物转化对天然药物进行结构修饰的研究进展[J].天然产物研究与开发,2012(6):843.
- [28]陆有根,余伯阳.微生物转化青蒿素为9α-羟基青蒿素的条件优化[J].药物生物技术,2001,8(2):90.
- 中药资源
- 中药资源化学
- 中药资源循环利用
Chinese medicinal material(CMM) resources - resources chemistry of Chinese medicinal materials(RCCMM)
- recycling utilization of CMM
- 段金廒
- 宿树兰
- 郭盛
- 江曙
- 刘培
- 严辉
- 钱大玮
- 朱华旭
- 唐于平
- 吴启南
DUAN Jin-ao- SU Shu-lan
- GUO Sheng
- JIANG Shu
- LIU Pei
- YAN Hui
- QIAN Da-wei
- ZHU Hua-xu
- TANG Yu-ping
- WU Qi-nan
- Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization
- and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine
- Nanjing University of Chinese Medicine
- 段金廒
- 宿树兰
- 郭盛
- 江曙
- 刘培
- 严辉
- 钱大玮
- 朱华旭
- 唐于平
- 吴启南
DUAN Jin-ao- SU Shu-lan
- GUO Sheng
- JIANG Shu
- LIU Pei
- YAN Hui
- QIAN Da-wei
- ZHU Hua-xu
- TANG Yu-ping
- WU Qi-nan
- Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization
- and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine
- Nanjing University of Chinese Medicine