中国中药杂志

2017, v.42(24) 4707-4715

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黄檀属植物新黄酮类化学成分与药理活性研究进展
Neoflavonoids and their pharmacological activities in Dalbergia genus

刘荣华;林帅;张普照;陈兰英;黄慧莲;梅丹仪;胡少杰;邵峰;
LIU Rong-hua;LIN Shuai;ZHANG Pu-zhao;CHEN Lan-ying;HUANG Hui-lian;MEI Dan-yi;HU Shao-jie;SHAO Feng;Jiangxi University of Traditional Chinese Medicine;

摘要(Abstract):

新黄酮类化学成分(neoflavonoids)是黄檀属Dalbergia植物的一类特征性成分。据文献统计,迄今已有59个新黄酮类成分从该属植物中分离得到,按其基本骨架,主要分为黄檀酚类、黄檀醌类、黄檀内酯类、苯酰苯类及其他类。现代研究表明,该类成分具有抗骨质疏松、抗雄性激素、抗炎、抗肿瘤、抗过敏、抗氧化等多种生物活性。该文对黄檀属植物新黄酮类化学成分与药理活性进行综述,以期为黄檀属植物综合利用与新药开发提供参考。
Neoflavonoids are a kind of characteristic components in the Dalbergia genus. Based on the previous researches,59 neoflavonoids have been obtained from the Dalbergia genus. According to their molecular skeleton,the neoflavonoids can be divided intodalbergiphenols,dalbergiones,dalbergins,benzophenones and other types. Modern research shows that neoflavonoids displayed a variety of pharmacological activities,such as anti-osteoporosis,anti-inflammatory,antitumor,anti-androgen,anti-allergic,antioxidation etc. This paper reviewed neoflavonoids and their pharmacological functions,which could provide the valuable reference for comprehensive utilization and new drug development in the Dalbergia genus.

关键词(KeyWords): 黄檀属;新黄酮;化学成分;药理活性
Dalbergia;neoflavonoids;chemical constituents;pharmacological activities

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(81360629,81660676);; 江西省自然科学基金项目(20171BAB205096);; 江西中医药大学校级研究生创新专项(JZYC17S042)

作者(Author): 刘荣华;林帅;张普照;陈兰英;黄慧莲;梅丹仪;胡少杰;邵峰;
LIU Rong-hua;LIN Shuai;ZHANG Pu-zhao;CHEN Lan-ying;HUANG Hui-lian;MEI Dan-yi;HU Shao-jie;SHAO Feng;Jiangxi University of Traditional Chinese Medicine;

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