中国中药杂志

2005, (13) 1006-1008

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荫风轮总苷对动物子宫作用的研究
Research on effect of total saponins of Yinfenglun on uterine

彭代银,刘青云,戴敏,訾晓梅,徐先祥
PENG Dai-yin, LIU Qing-yun, DAI Min, ZI Xiao-mei, XU Xian-xiang (Anhui College of Traditional Chinese Medicine, Hefei 230038, China)

摘要(Abstract):

目的:研究荫风轮总苷对子宫功能的影响。方法:无菌植入异物造成大鼠子宫炎症模型,观察荫风轮总苷的治疗作用;于大鼠离体子宫和家兔在体子宫观察其对子宫活动力和子宫收缩幅度的影响;并测定了荫风轮总苷对大鼠子宫重量和血清中雌二醇、黄体酮含量的影响。结果:荫风轮总苷有增强子宫收缩能力,且对在体子宫的作用维持时间较长,能显著增加子宫重量,有减轻子宫炎症作用的趋势,对雌激素水平有升高趋势,对孕激素水平无显著影响。结论:荫风轮总苷对子宫的作用是用于治疗子宫出血的重要药理基础。
Objective: To research the effect of total saponins of Yinfenglun on uterine. Method: Models of uterine inflammation were established to observe the effect of total saponins of Yinfenglun. Uterine contractive effects were studied on rats in vitro and on rabbit in vivo. Weight of uterus and levels of estrogen and progestogen were determined. Result: Total Saponins of Yinfenglun had the ameliorated tendency to metritis of model rats,and increased the contractive range and motorricity of uterine of rats in vitro and of rabbit in vivo .The effect to uterus in vivo maintained longer, total saponins of Yinfenglun could increase the weight of uterus and have a increased tendency on the content of estrogen, but not the level of progestogen. Conclusion: There are obvious effects on uterine of total saponins of Yinfenglun, which are related to its clinical use.

关键词(KeyWords): 荫风轮总苷;子宫;药理作用
total saponins of Yinfenglun; uterine; effect

Abstract:

Keywords:

基金项目(Foundation): 安徽省“九五”科技攻关项目(96130104)

作者(Author): 彭代银,刘青云,戴敏,訾晓梅,徐先祥
PENG Dai-yin, LIU Qing-yun, DAI Min, ZI Xiao-mei, XU Xian-xiang (Anhui College of Traditional Chinese Medicine, Hefei 230038, China)

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