中国中药杂志

2011, v.36(08) 1075-1078

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四物汤多成分关系的博弈描述
Describe relationship among multi-components of Siwu decoction using game theory

刘明;马增春;梁乾德;王宇光;谭洪玲;肖成荣;肖瑞;张伯礼;高月;
LIU Ming1,MA Zengchun1,LIANG Qiande1,WANG Yuguang1,TAN Hongling1,XIAO Chengrong1,XIAO Rui1,ZHANG Boli2,GAO Yue1(1.Institute of Radiation Medicine,Academy of Military Medical Sciences,Beijing 100850,China;2.Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China;3.Medical Library of PLA,Beijing 100039,China)

摘要(Abstract):

博弈论是复杂系统理论的重要组成部分,特别适合描述双方或者多方合作解决问题或者对抗求得平衡的复杂问题。中医的方剂学说包含了博奕论思想的多种涵义。本研究建立四物汤的多方博弈模型,并应用于几种不同配比的四物汤药效分析。首先应用模糊集合进行四物汤多成分交互分析,得到熟地、当归、川芎、白芍对于实验靶点的隶属度函数,然后将其作为博弈模型的收益函数,建立四物汤的多方博弈模型,应用于3种不同配比的四物汤药效分析。根据实验所选取的靶点和博弈模型,《太平惠民和剂局方》的四物汤配比是最优值之一。
Game theory is an important component of complex system theory,specially used in describing bilateral or multiple cooperation and confrontation.Traditional Chinese medicine(TCM) prescription doctrines cover multiple connotation of game theory.Firstly multi-components of Siwu decoction were analyzed by using fuzzy set to get the membership functions.Then the revenue function was contructed and build the Siwu decoction′s multi-player game model was built.Lastly the three kinds of different combinations Siwu decoction efficacy were analyzed by using the model to get the best compositions.

关键词(KeyWords): 四物汤;博弈;模糊集合;隶属度函数;收益函数
Siwu decoction;game theory;fuzzy set;membership function;revenue function

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(30730112,81001699)

作者(Authors): 刘明;马增春;梁乾德;王宇光;谭洪玲;肖成荣;肖瑞;张伯礼;高月;
LIU Ming1,MA Zengchun1,LIANG Qiande1,WANG Yuguang1,TAN Hongling1,XIAO Chengrong1,XIAO Rui1,ZHANG Boli2,GAO Yue1(1.Institute of Radiation Medicine,Academy of Military Medical Sciences,Beijing 100850,China;2.Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China;3.Medical Library of PLA,Beijing 100039,China)

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