李先端,仝燕,马振山,王琳
LI Xian-duan, TONG Yan, MA Zhen-shan, WANG Lin (Institute of Chinese Materia Medica, Academy of Traditional Chinese Medicine, Beijing 100700, China)

• 1:中国中医研究院中药研究所
• 2:中国中医研究院中药研究所
• 3:中国中医研究院中药研究所
• 4:中国中医研究院中药研究所 北京100700

摘要(Abstract)：

目的 :建立银黄狼消颗粒质量标准 ;方法 :采用薄层层析定性 ,反相高效液相定量 ;结果 :建立金银花、青蒿、三七、紫草、山茱萸的鉴别方法 ,大黄中大黄酚的含量测定法。结论 :经方法学考察和 3批样品验证 ,方法准确 ,简便灵敏 ,可作为本制剂质量标准 ,并供其他复方制剂的参考。
Objective: To establish the quality standard of Yinhuang Langxiao granule. Method: The Panax notoginseng, Arnebia euchromq,Cornus officinalis,Lonicera japonica,Artemisiae annua were identified by TLC. The content of chrysophanol in granule was determined by HPLC. Result: Spots of samples on TLC can be well separated and the method had good specificity. The average recovery of chrysophanol was 98.7% and RSD was 0.67%. Conclusion: An acurate,simple and effective quality-controlling method has been developed, which can be used for quality control for Yinhuang Langxiao granule.

关键词(KeyWords)： 银黄狼消颗粒;金银花薄层;青蒿薄层;高效液相法;大黄酚含量测定
Yinhuang Langxiao granule; TLC; HPLC; chrysophanol

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 李先端,仝燕,马振山,王琳
LI Xian-duan, TONG Yan, MA Zhen-shan, WANG Lin (Institute of Chinese Materia Medica, Academy of Traditional Chinese Medicine, Beijing 100700, China)

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DOI:

参考文献(References)：

• [1]　中国药典.一部.2000.10,22,158,177,280.
• [2]　沙世炎,徐礼,严敏如,等.中草药有效成分分析法.北京:人民卫生出版社,1981.151.
• [3]　罗文毓,江　萍.大黄中五种蒽醌衍生物的HPLC测定.药物分析杂志,1989,9(5):259.