中国中药杂志

2017, v.42(01) 20-28

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岗梅的化学成分和药理作用研究进展
A phytochemical and pharmacological advance on Ilex asprella

杜冰曌;杨鑫瑶;冯晓;尹旭;张和新歌;赵凤;高增平;屠鹏飞;柴兴云;
DU Bing-zhao;YANG Xin-yao;FENG Xiao;YIN Xu;ZHANG He-xin-ge;ZHAO Feng;GAO Zeng-ping;TU Peng-fei;CHAI Xing-yun;Modern Research Center for Traditional Chinese Medicine,School of Chinese Materia Medica,Beijing University of Chinese Medicine;

摘要(Abstract):

岭南特色药材岗梅为冬青科冬青属梅叶冬青的根和茎,具有清热解毒、生津止渴、利咽消肿、散瘀止痛之功效,民间多用于治疗风热感冒、急慢性咽喉炎、咽喉肿痛等疾病。现代研究表明,岗梅的化学成分以三萜皂苷为主,也含有一定的酚酸和少量甾体及单萜。药理研究显示,岗梅提取物具有抗炎、抗病毒、抗肿瘤、调节脂质代谢等活性。该文对岗梅的传统应用、化学成分及药理活性进行整理,以期为系统的药效物质研究、质量标准提升及资源进一步开发利用提供参考。
Ilex asprella is one of representative medicinal plants in South of the Five Ridges of China. The roots and rhizomes of I. asprella have the effects of clearing heat and detoxifying,stimulating salvia,and reducing thirst,which has been used to treat windheat cold,acute and chronic pharyngitis,and sore throat. Contemporary studies showed that I. asprella contains the major triterpenoids and glycosides,phenolic acids,and minor steroids. The extracts and compounds show activities of anti-inflammatory,antiviral,antitumor,and regulating lipid metabolism. The present paper summarizes a phytochemical and pharmacological advance on this species to provide reference for clarification of its pharmacologically active ingredients,quality evaluation,and further explorations.

关键词(KeyWords): 岗梅;冬青属;三萜皂苷;药理活性;综述
Ilex asprella;triterpenoids;triterpenoid saponin;pharmacological activity;review

Abstract:

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基金项目(Foundation): 国家自然科学基金项目(81473426,81303309)

作者(Author): 杜冰曌;杨鑫瑶;冯晓;尹旭;张和新歌;赵凤;高增平;屠鹏飞;柴兴云;
DU Bing-zhao;YANG Xin-yao;FENG Xiao;YIN Xu;ZHANG He-xin-ge;ZHAO Feng;GAO Zeng-ping;TU Peng-fei;CHAI Xing-yun;Modern Research Center for Traditional Chinese Medicine,School of Chinese Materia Medica,Beijing University of Chinese Medicine;

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