中国中药杂志

2007, (24) 2600-2603

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

麻杏石甘汤麻黄碱含量影响因素的研究
Studies on factors influencing on ephedrine contents in Maxing Shigan decoction

梁光义;贺祝英;武孔云;靳凤云;李星;冯华;
LIANG Guang-yi1,HE Zhu-ying2,WU Kong-yun3,JIN Feng-yun2,LI Xing2,FENG Hua2(1.The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences,Guiyang 550002,China;2.Guiyang College of Traditional Chinese Medicine,Guiyang 550002,China;3.Guiyang College,Guiyang 550003,China)

摘要(Abstract):

目的:考察麻杏石甘汤中不同组方配伍对麻黄碱含量的影响。方法:采用混料均匀设计对麻杏石甘汤进行拆方研究,对实验数据进行逐步回归分析处理,对回归方程的各项系数进行偏相关检验;并进行了验证实验。结果:回归方程Y=4.367 193 47+7.752 707 437X2+1.255 719 704 1X3有意义(r=0.856 64,P=0.018 9),通过回归方程和偏相关检验,麻杏石甘汤传统汤剂中麻黄碱含量的主要影响因素为苦杏仁和石膏,其中苦杏仁的影响为极显著、石膏的影响为显著。结论:麻杏石甘汤传统汤剂中的苦杏仁以及石膏共同作用,影响麻杏石甘汤传统汤剂中麻黄碱的含量,其量效关系为正相关。
Objective: To investigate the factors influencing on the ephedrine contents in different compositions of Maxingshigan decoction.Method: Adopt mixed uniform design to dismantle recipes,employ the stepping regression analysis to deal with experimental statistics,use the partial correlational analysis to analyze the correlation coefficients and the results were validated.Result: The regressive equation was of significance,that is Y=4.367 193 47+7.752 707 437X1+1.255 719 704 1X3(r=0.855 64,P=0.018 9).The main influencing factors on ephedrine content in Maxingshigan decoction were gypsum and amygdalin.The influent factor of amygdalin on ephedrine content had great significance,and gypsum had significance.Conclusion: The collective effects of amygdalin and gypsum affect the content of ephedrine in Maxing Shigan decoction which the content-effect relationship was in direct correlation.

关键词(KeyWords): 麻杏石甘汤;混料均匀设计;盐酸麻黄碱
Maxing Shigan decoction;mixed uniform design;ephedrine hydrochloride

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(30460154)

作者(Author): 梁光义;贺祝英;武孔云;靳凤云;李星;冯华;
LIANG Guang-yi1,HE Zhu-ying2,WU Kong-yun3,JIN Feng-yun2,LI Xing2,FENG Hua2(1.The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences,Guiyang 550002,China;2.Guiyang College of Traditional Chinese Medicine,Guiyang 550002,China;3.Guiyang College,Guiyang 550003,China)

Email:

DOI:

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享