中国中药杂志

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斑蝥不同炮制品药理作用的研究
Studies on the Pharmacological Action of Various Processed Mylabris phalerata Pallas

张振凌,王正益,孙水平,李军,张广强,苗明三
Zhang Zhenling, Wang Zhengyi, Sun Shuiping, Li Jun, Zhang Guangqiang Miao Mingsan (Henan College of Traditional Chinese Medicine, Zhengzhou 450003)

摘要(Abstract):

比较了斑蝥去头足翅前后的生品、米炒品、碱处理新法炮制品的急性毒性、亚急性毒性及体内外抗肿瘤作用。结果表明,炮制品毒性小于生品,去头足翅后毒性增大,碱处理炮制新法优于药典米炒法。
We have compared the acute toxicity, sub-acute toxicity and in vitro and in vivo anti-tumor action of the rude drug, stir-fried with rice, and alkali-processed drugs of Mylabris phalerata before and after removing the head, feet and wings. The results indicate that the toxicity of the processed drugs is lower than that of the rude ones; the toxicity becomes higher without head, feet, and wings;and the alkali-processing method is better than stir-frying with rice recorded in the pharmacopeia.

关键词(KeyWords): 斑蝥;米炒;碱处理;毒性;抗肿瘤
Mylabris phalerata; stir-frying with rice; alkali-processing; toxicity; antitumor

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作者(Author): 张振凌,王正益,孙水平,李军,张广强,苗明三
Zhang Zhenling, Wang Zhengyi, Sun Shuiping, Li Jun, Zhang Guangqiang Miao Mingsan (Henan College of Traditional Chinese Medicine, Zhengzhou 450003)

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