中国中药杂志

2015, v.40(13) 2518-2523

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近10年甾体皂苷的生物活性研究进展
Research progress of bioactivity of steroidal saponins in recent ten years

刘星;余江丽;刘敏;舒积成;黄慧莲;
LIU Xing;YU Jiang-li;LIU Min;SHU Ji-cheng;HUANG Hui-lian;Jiangxi University of Traditional Chinese Medicine;

摘要(Abstract):

甾体皂苷具有广泛的药理作用和生物活性,如抗肿瘤、抗真菌、降血糖、免疫调节、驱虫等。近10年来,从天然植物中又发现一些新结构的甾体皂苷类化合物,它们具有强度不一的新活性。为了加快甾体皂苷化合物的药物创新研究,该文概述此类化合物的研究新进展。
Steroidal saponins have a wide range of pharmacological effects and biological activities,such as anti-tumor,antifungal,hypoglycemic,immune regulation,insecticides,etc. In the last ten years,some new structures of steroidal saponins compounds were found from natural plants,they have some new and different activities. In order to accelerate the research on the drug innovation of steroidal saponins,we summarized the new progress of the research on such compounds.

关键词(KeyWords): 甾体皂苷;药理作用;生物活性
steroidal saponins;pharmacological effects;biological activity

Abstract:

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基金项目(Foundation): 江西省卫生厅中医药科研计划课题(2013A003);; 江西省教育厅科学技术研究项目(GJJ13596);; 国家自然科学基金项目(81160507,81660628)

作者(Author): 刘星;余江丽;刘敏;舒积成;黄慧莲;
LIU Xing;YU Jiang-li;LIU Min;SHU Ji-cheng;HUANG Hui-lian;Jiangxi University of Traditional Chinese Medicine;

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