中国中药杂志

2008, (12) 1371-1377

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人参皂苷Rb_1的药理活性研究进展
Advance of pharmacological study on ginsenoside Rb_1

贾继明;王宗权;吴立军;吴以岭;
JIA Ji-ming WANG Zong-quan WU Li-jun WU Yi-ling (1.School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shengyang 110016,China; 2.Hebei Province Traditional Chinese Medicine and Western Medicine Institute of Pharmaceutical,Shijiazhuang 050035,China)

摘要(Abstract):

人参皂苷Rb_1是人参二醇系皂苷的代表成分之一,属于达玛烷型三萜皂苷类化合物,主要分布于五加科植物中,具有多种生物活性。作者从心血管系统、抗衰老、逆转肿瘤细胞耐药、肿瘤化疗的辅助用药、促进周围神经再生等几个方面,对人参皂苷Rb_1近10年来的研究进展进行了综述。
Ginsenoside Rb_1 is a representative component of panaxadiol saponins,which belongs to dammarane-type tritepe- noid saponins and mainly exists in family araliaceae.It has been reported that ginsenoside Rb_1 has diverse biological activities.In this paper,the research development in recent decade on its pharmacological effects of cardiovascular system,anti-senility,reversing multi- drug resistance of tumor cells,adjuvant anti-cancer chemotherapy,promoting peripheral nerve regeneration,et al,are reviewed.

关键词(KeyWords): 人参皂苷Rb_1;药理活性;心血管系统;抗衰老
ginsenoside Rb_1;pharmacological study;cardiovascular system;anti-senility

Abstract:

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基金项目(Foundation): 国家重点基础研究发展计划项目(2005CB523301)

作者(Author): 贾继明;王宗权;吴立军;吴以岭;
JIA Ji-ming WANG Zong-quan WU Li-jun WU Yi-ling (1.School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shengyang 110016,China; 2.Hebei Province Traditional Chinese Medicine and Western Medicine Institute of Pharmaceutical,Shijiazhuang 050035,China)

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