中国中药杂志

2021, v.46(06) 1301-1326

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枣仁安神成方制剂的研究进展
Research advances of Zaoren Anshen prescription preparations

解满江;屠鹏飞;张庆英;
XIE Man-jiang;TU Peng-fei;ZHANG Qing-ying;State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines,School of Pharmaceutical Sciences,Health Science Center,Peking University;

摘要(Abstract):

枣仁安神成方制剂由炒酸枣仁、丹参和醋五味子制得,临床用于治疗心血不足引起的失眠、健忘、心烦、头晕及神经衰弱症见上述证候者。为了保障枣仁安神成方制剂临床用药的安全性、有效性和稳定性,近年来对其药效作用、物质基础及质量控制进行了较为广泛的研究,并取得了一定进展,但目前尚无针对枣仁安神成方制剂研究进展的综述。该文首次系统归纳总结了有关枣仁安神成方制剂质量标准、化学成分、药效作用和分析方法的研究进展,为枣仁安神成方制剂药效物质和质量控制的深入研究提供参考。
Zaoren Anshen prescription preparations(ZRASs), which are prepared from three traditional Chinese herb medicines, namely fried Zizyphi Spinosae Semen, Salvia Miltiorrhizae Radix et Rhizoma and vinegar-processed Schisandrae Chinensis Fructus, are a series of proprietary Chinese medicines for the treatment of insomnia, amnesia and dizzy in clinic. In recent years, pharmacodynamic effect, chemical constituents and quality control of ZRASs had been extensively studied for the purpose of ensuring their safety, efficacy and stability, and a great progress had been made. However, there is no review of the research advance of ZRASs up to date. The present review summarized the research advance of ZRASs in quality control standards, chemical constituents, pharmacodynamic effects, and chemical analysis for the first time, with the aim to provide a reference for further studies on the effective constituents and quality control of ZRASs.

关键词(KeyWords): 枣仁安神方;中成药;化学成分;药效作用;分析方法;质量控制
Zaoren Anshen prescription;proprietary Chinese medicine;chemical constituent;pharmacodynamic effect;analytic procedure;quality control

Abstract:

Keywords:

基金项目(Foundation): 国家重点研发计划项目(2018YFC1707300)

作者(Author): 解满江;屠鹏飞;张庆英;
XIE Man-jiang;TU Peng-fei;ZHANG Qing-ying;State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines,School of Pharmaceutical Sciences,Health Science Center,Peking University;

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DOI: 10.19540/j.cnki.cjcmm.20201228.601

参考文献(References):

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