中国中药杂志

2007, (17) 1740-1743

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川芎中含阿魏酸效应组分的提取、纯化工艺研究
Studies on extraction and purification of active parts of ferulic acid from Ligusticun chuanxiong

洪燕龙;徐德生;冯怡;袁莹;
HONG Yan-long,XU De-sheng,FENG Yi,YUAN Ying(1.Shuguang Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China;2.School of Pharmacy,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)

摘要(Abstract):

目的:对川芎中含阿魏酸效应组分的提取、纯化工艺进行优化研究。方法:以阿魏酸为主要指标,采用单因素及正交试验设计考察提取工艺参数的最佳组合;采用单因素试验考察大孔树脂吸附法的纯化工艺参数。结果:纯化后含阿魏酸效应组分的出膏率为1.67%,其中含阿魏酸5.82%。结论:本实验研究为川芎药材及其制剂的开发提供有益的实验依据。
Objective:To study on the process of extraction and purification of active parts from Ligusticun chuanxiong.Method:The processes of extraction and purification of active parts of ferulic acid were optimized by direct comparison and orthogonal design.Result:Extract rate of active parts of ferulic acid was 1.67% and the content of ferulic acid was 5.82%.Conclusion:Active parts of ferulic acid from L.chuanxiong were extracted and purified effectively.

关键词(KeyWords): 川芎;阿魏酸;提取;纯化
Ligusticun chuanxiong;ferulic acid;extraction;purification

Abstract:

Keywords:

基金项目(Foundation): 上海市重点学科建设项目资助(T0301)

作者(Authors): 洪燕龙;徐德生;冯怡;袁莹;
HONG Yan-long,XU De-sheng,FENG Yi,YUAN Ying(1.Shuguang Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China;2.School of Pharmacy,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)

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