中国中药杂志

2010, v.35(13) 1720-1722

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白花油麻藤化学成分研究
Chemical constituents of stem barks of Mucuna birdwoodiana

巩婷;王东晓;刘屏;陈若芸;
GONG Ting1,WANG Dongxiao2,Liu Ping2,CHEN Ruoyun1(1.Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100050,China;2.Research Institute for Clinical Pharmacology,General Hospital of PLA,Beijing 100853,China)

摘要(Abstract):

目的:研究白花油麻藤Mucuna birdwoodiana藤茎的化学成分。方法:采用柱色谱方法分离化合物,采用谱学方法鉴定其结构。结果:分离并鉴定了11个化合物。3′-methoxycoumestrol(1),芒柄花素(formononetin,2),染料木素(genisten,3),8-甲雷杜辛(8-O-methylretusin,4),7,3′-二羟基-5′-甲氧基异黄酮(5),大黄酚(chrysophanol,6),丁香脂素(syringaresinol,7),表木栓醇(epifriedelanol,8),羽扇豆醇(lupeol,9)。结论:除化合物2,3,8,9外,以上化合物均为首次从该属植物分得。
Eleven compounds were isolated from the stem bark of Mucuna birdwoodiana.Their structures were elucidated by various spectral analyses and identified as 3′-methoxycoumestrol(1),formononetin(2),genisten(3),8-O-methylretusin(4),7,3′-dihydroxy-5′-methoxyisoflavone(5),chrysophanol(6),syringaresinol(7),epifriedelanol(8),lupeol(9),respectively.All compounds except 2,3,8 and 9 were isolated from the genus for the first time.

关键词(KeyWords): 白花油麻藤;油麻藤属;化学成分;异黄酮
Mucuna birdwoodiana;Mucuna;contituents;isoflavone

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基金项目(Foundation): 国家自然科学基金项目(30500650)

作者(Author): 巩婷;王东晓;刘屏;陈若芸;
GONG Ting1,WANG Dongxiao2,Liu Ping2,CHEN Ruoyun1(1.Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100050,China;2.Research Institute for Clinical Pharmacology,General Hospital of PLA,Beijing 100853,China)

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