龙海林;李康强;许文东;傅玉萍;
LONG Hai-lin;LI Kang-qiang;XU Wen-dong;FU Yu-ping;National Engineer Research Center for the Modernization of Extraction and Separation of Traditional Chinese Medicine,Guangzhou Hanfang Pharmaceutical Co.,Ltd.;

• 1:中药提取分离过程现代化国家工程研究中心广州白云山汉方现代药业有限公司

摘要(Abstract)：

综合运用各种色谱分离技术对海绵共生真菌Emericella variecolor的固体大米培养基发酵产物进行化学成分研究,利用各种波谱技术进行化学结构鉴定。结果从该真菌的发酵产物中分离得到6个单体化合物,分别鉴定为(+)-2-acetyl-dihydroterrein(1),(+)-3-acetyl-dihydroterrein(2),anditomin(3),andilesin A(4),andilesin C(5),andilesin B(6)。其中化合物1和2为新化合物。
We have carried out the investigation on a sponge-derived fungus,which was identified as Emericella variecolor from the south sea of China. Two new chemical constituents,( +)-2-acetyl-dihydroterrein( 1) and( +)-3-acetyl-dihydroterrein( 2),with four known compounds,anditomin( 3),andilesin A( 4),andilesin C( 5) and andilesin B( 6),were isolated from this fungus by column chromatography over silica gel,Sephadex LH-20,and ODS. The structures of 1 and 2 were elucidated by spectroscopic methods including NMR,HR-ESI-MS,and CD.

关键词(KeyWords)： 海绵共生真菌;Emericella variecolor;化学成分
sponge-derived fungus;Emericella variecolor;chemical constituents

Abstract:

Keywords:

基金项目(Foundation): 广东省省级科技计划项目(2015B020234001)

作者(Authors): 龙海林;李康强;许文东;傅玉萍;
LONG Hai-lin;LI Kang-qiang;XU Wen-dong;FU Yu-ping;National Engineer Research Center for the Modernization of Extraction and Separation of Traditional Chinese Medicine,Guangzhou Hanfang Pharmaceutical Co.,Ltd.;

DOI: 10.19540/j.cnki.cjcmm.2017.0131

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