尚小雅;李帅;王映红;王素娟;杨永春;石建功;
SHANG Xiao-ya1,2,LI Shuai1,WANG Su-juan1,YANG Yong-chun1,SHI Jian-gong1(1.Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education,Beijing 100050,China;2.College of Arts & Science of Beijing Union University,Beijing Key Laboratory of Bioactive Substances and Functional Foods,Beijing 100083,China)

• 1:中国医学科学院中国协和医科大学药物研究所中草药物质基础与资源利用教育部重点实验室
• 2:中国医学科学院中国协和医科大学药物研究所中草药物质基础与资源利用教育部重点实验室
• 3:中国医学科学院中国协和医科大学药物研究所中草药物质基础与资源利用教育部重点实验室
• 4:中国医学科学院中国协和医科大学药物研究所中草药物质基础与资源利用教育部重点实验室

摘要(Abstract)：

目的:研究红绒毛羊蹄甲Bauhinia aurea的化学成分。方法:应用各种色谱技术进行分离纯化,用MS和NMR分析确定化合物结构。结果:从红绒毛羊蹄甲90%乙醇提取物的醋酸乙酯萃取部位中分离得到8个化合物,分别鉴定为异黄杞苷(1)、落新妇苷(2)、新落新妇苷(3)、异落新妇苷(4)、新异落新妇苷(5)、(2R,3S)-儿茶精6)、(2R,3R)-表儿茶精(7)和(2R,3R)-3-O-没食子酰表儿茶精(8)。结论:除化合物2,6和8外,其余5个化合物均属首次从该属植物中发现。
Objective: To study the chemical constituents of Bauhinia aurea.Method: The compounds were isolated by column chromatography over silica gel,reversed-phase RP-18,and Sephadex LH-20.MS and NMR spectroscopic methods were used to determine structures of purified compounds.Result: Eight compounds were isolated from the ethyl acetate soluble fraction of the ethanolic extract and their structures were elucidated as isoengeletin(1),astilbin (2),neoastilbin(3),isoastilbin(4),neoisoastilbin(5),(+)-catechin(6),(-)-epicatechin(7) and(-)-epicatechin 3-O-gallate(8).Conclusion: Five compounds were isolated from this genus for the first time except for 2,6 and 8.

关键词(KeyWords)： 豆科;红绒毛羊蹄甲;二氢黄酮醇苷;黄烷-3-醇
Leguminosae;Bauhinia aurea;dihydroflavonol glycosides;flavan-3-ols

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(20432030);; 新世纪优秀人才支持计划(NCET)

作者(Author): 尚小雅;李帅;王映红;王素娟;杨永春;石建功;
SHANG Xiao-ya1,2,LI Shuai1,WANG Su-juan1,YANG Yong-chun1,SHI Jian-gong1(1.Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education,Beijing 100050,China;2.College of Arts & Science of Beijing Union University,Beijing Key Laboratory of Bioactive Substances and Functional Foods,Beijing 100083,China)

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DOI:

参考文献(References)：

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