确生;赵玉英;周勇;张庆英;
QUE Sheng1,2,ZHAO Yuying1,ZHOU Yong1,ZHANG Qingying1(1.Department of Natural Medicines,School of Pharmaceutical Sciences,Peking University Health Science Center,Beijing 100191,China;2.Department of Chemistry,Minorities Teachers College,Qinghai Teachers University,Xining 810008,China)

• 1:青海师范大学民族师范学院化学系
• 2:北京大学药学院天然药物学系

摘要(Abstract)：

目的:研究藏药小叶毛球莸的化学成分。方法:采用溶剂法和色谱法提取分离化学成分,并用波谱方法鉴定化学成分结构。结果:从藏药小叶毛球莸中分离得到2个对映-贝壳杉烯型二萜类化合物:冬凌草甲素(1)和nodosin(2),并首次报道了该两个化合物在甲醇(CD3OD)中的1H和13C-NMR数据。结论:对映-贝壳杉烯型二萜类化合物为首次从莸属植物中分离得到。
Objective: To study the chemical constituents of Tibetan medicine Caryopteris toroetii.Method: The crude drug was extracted with 95% EtOH and isolated by repeated chromatographic methods.The structures of the isolated compounds were elucidated on the basis of spectral analysis.Result: Two en-kaurene diterpenoid compounds: oridonin(1) and nodosin(2),were obtained from C.toroetii and their 1H and 13C-NMR data in CD3OD were reported for the first time.Conclusion: The en-kaurene diterpenoid compounds were obtained from genus Caryopteris for the first time.

关键词(KeyWords)： 藏药;莸属;小叶毛球莸;对映-贝壳杉烯型二萜;冬凌草甲素;nodosin
Tibetan medicine;Caryopteris;Caryopteris toroetii;en-kaurene diterpenoid;oridonin;nodosin

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(20872006)

作者(Authors): 确生;赵玉英;周勇;张庆英;
QUE Sheng1,2,ZHAO Yuying1,ZHOU Yong1,ZHANG Qingying1(1.Department of Natural Medicines,School of Pharmaceutical Sciences,Peking University Health Science Center,Beijing 100191,China;2.Department of Chemistry,Minorities Teachers College,Qinghai Teachers University,Xining 810008,China)

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