红花石蒜生物碱化学成分的研究Amaryllidaceae alkaloids from Lycoris radiata
胡疆;刘雁;李强;张丽芳;景年华;史俊友;吕涛;殷斯;彭天凤;郝珊瑚;
摘要(Abstract)：
对红花石蒜Lycoris radiata鳞茎的生物碱类成分进行研究。采用硅胶、反向硅胶、凝胶及MCI-gel树脂等多种色谱技术,对红花石蒜的生物碱进行分离和纯化,并通过1H-NMR,13C-NMR和MS等波谱方法鉴定化合物的结构。从该植物鳞茎70%乙醇提取液的氯仿萃取部分中分离得到9个amaryllidaceae类生物碱,分别鉴定为(+)-N-methoxylcarbonyl-1,2-methylenedioxyl-isocorydione(1),isocorydione(2),8-demethyl-dehydrocrebanine(3),(+)-3-hydroxy-anhydrolycorine N-oxide(4),vasconine(5),pancratinine D(6),yemenine A(7),11-O-acetylhaemanthamine(8)和5,6-dihydro-5-methyl-2-hydroxyphenanthridine(9)。其中,化合物1为新化合物,化合物2~9为首次从该植物中分离得到。
关键词(KeyWords)： 红花石蒜;石蒜科;化学成分;生物碱类
基金项目(Foundation): 国家自然科学基金项目(31760341);; 云南省应用基础研究计划项目(2016FD080);; 云南省高校科技创新团队项目(云教科(2014)14号)
作者(Author): 胡疆;刘雁;李强;张丽芳;景年华;史俊友;吕涛;殷斯;彭天凤;郝珊瑚;
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