中国中药杂志

2014, v.39(20) 3955-3957

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

苁蓉总苷胶囊HPLC指纹图谱研究
Study on HPLC fingerprint of Congrong Zonggan capsule

杨素德;王伟;李家春;萧伟;
YANG Su-de;WANG Wei;LI Jia-chun;XIAO Wei;Jangsu Kanion Pharmaceutical Co. ,Ltd.;State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process;

摘要(Abstract):

该文建立苁蓉总苷胶囊的HPLC指纹图谱,为其质量评价提供依据。以毛蕊花糖苷为参照物,采用高效液相色谱法,对苁蓉总苷胶囊进行了指纹图谱分析。色谱条件:Waters C18色谱柱(4.6 mm×150 mm,5μm);流动相甲醇-0.1%甲酸溶液梯度洗脱;流速1.0 m L·min-1;检测波长330 nm;柱温30℃。该方法精密度高、重复性好,所测样品中的13个成分均达到基线分离,并且15批成品指纹图谱相似度在0.95以上。该方法准确、可行,是一种简便、有效的中药质量评价手段。
HPLC fingerprint of Congrong Zonggan capsule was established in order to provide basis for quality evaluation. With acteoside as the reference,HPLC was adopted for fingerprint analysis on Congrong Zonggan capsule. The chromatographic conditions were as follows. Waters C18column( 4. 6 mm × 150 mm,5 μm) was used,with methyl alcohol-0. 1% formic acid as the mobile phase for gradient elution at the flow rate of 1. 0 m L·min- 1. The detection wavelength was 330 nm,and the column temperature was 30 ℃.This method was highly accurate and reproducible. All of the 13 components in tested samples reached the baseline resolved peak,and15 batches of finished products showed the similarity of above 0. 95. The method was accurate and feasible and could be used as a simple and effective method to evaluate the quality of the traditional Chinese medicines.

关键词(KeyWords): 苁蓉总苷胶囊;高效液相色谱法;指纹图谱;松果菊苷
Congrong Zonggan capsule;HPLC;fingerprint;echinacoside

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 杨素德;王伟;李家春;萧伟;
YANG Su-de;WANG Wei;LI Jia-chun;XIAO Wei;Jangsu Kanion Pharmaceutical Co. ,Ltd.;State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process;

Email:

DOI:

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享