中国中药杂志

1992, (07) 424-426+447

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

高效液相色谱法测定青藤碱血药浓度及药物动力学研究
Studies on Pharmacokinetics of Sinomenine by HPLC

罗顺德,蔡鸿生,张先州,潘细贵
Lou Shunde, Cai Hongsheng, Zhang Xianzhou and Pan Xigui(Hubei Medical College, Wuchang 430060)

摘要(Abstract):

用反相高效液相色谱外标法,测定单剂量(20mg/kg)静脉注射青藤碱后不同时间兔体内血药浓度,并用Marguardt法迭代拟合,结果符合二室模型。
Pharmacokinetics of sinomenine in rabbit was studied by reverse-phase HPLC method. After iv injection of 20mg/kg of sinomenine to rabbits, the pharmacokinetic characteristics were found to fit a two-compartment open model.

关键词(KeyWords): 青藤碱;高效液相色谱;药代动力学
sinomenine; HPLC; pharmacokinetics

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 罗顺德,蔡鸿生,张先州,潘细贵
Lou Shunde, Cai Hongsheng, Zhang Xianzhou and Pan Xigui(Hubei Medical College, Wuchang 430060)

Email:

DOI:

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享