中国中药杂志

2019, v.44(01) 34-39

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中药对肠道菌群的调节作用
Regulatory effect of traditional Chinese medicine on intestinal microbiota

于岚;邢志凯;米双利;吴霞;
YU Lan;XING Zhi-kai;MI Shuang-li;WU Xia;Key Laboratory of Collateral Disease Theory Research,School of Traditional Chinese Medicine,Capital Medical University;Key Laboratory of Precision Genomic Medicine,Beijing Institute of Genomics,Chinese Academy of Sciences;

摘要(Abstract):

肠道菌群作为人体庞大的微生态系统与许多疾病的发生密切相关。临床研究和动物实验表明,中药可维持肠道微生态的平衡,对肠道菌群的调节作用也逐渐被阐释。该文通过归纳总结近5年来的文献,以中药对肠道菌群的调节作用为线索,从肠道菌群的研究方法和中药有效成分、提取物及复方调节肠道菌群的相关研究等方面进行了综述,为中药在肠道菌群调节方面的研究与开发提供参考。
As a large micro-ecosystem in the human body,the intestinal microbiota is closely associated with the occurrence of many diseases.The clinical investigations and animal experiments have showed that traditional Chinese medicine(TCM) could maintain the balance of the intestinal micro-ecological system.This review summarized the research methods and literatures on the regulation effects of TCM,including different effective ingredients,extracts and Chinese herbal formulae,on intestinal microflora in recent five years,in order to provide a reference for the further research and development of TCM.

关键词(KeyWords): 中药;有效成分;提取物;中药复方;肠道菌群;调节作用
traditional Chinese medicine;effective ingredients;extracts;Chinese herbal formulae;intestinal microflora;regulation effect

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金面上项目(81773999);; 北京高等学校高水平人才交叉培养“实培计划”毕业设计(科研类)项目

作者(Authors): 于岚;邢志凯;米双利;吴霞;
YU Lan;XING Zhi-kai;MI Shuang-li;WU Xia;Key Laboratory of Collateral Disease Theory Research,School of Traditional Chinese Medicine,Capital Medical University;Key Laboratory of Precision Genomic Medicine,Beijing Institute of Genomics,Chinese Academy of Sciences;

DOI: 10.19540/j.cnki.cjcmm.20181101.013

参考文献(References):

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