中国中药杂志

2012, v.37(18) 2820-2823

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灯盏细辛注射液药理和毒理作用研究进展
Progresses on pharmacological and toxicological effects of Dengzhanxixin injection

郭婷;黎元元;
GUO Ting1,LI Yuan-yuan2(1.Yunnan Biovalley Dengzhanhua Pharmaceutical Co.,Ltd.,Kunming 652300,China; 2.Institute of Basic Research in Clinical Medcine,China Academy of Chinese Medical Sciences,Beijing 100700,China)

摘要(Abstract):

灯盏细辛注射液是灯盏细辛经提取酚酸类成分制成的灭菌水溶液,现收载于2010年版《中国药典》中,广泛应用于临床。灯盏细辛注射液主要具有舒张血管,改善微循环,提高心脑供血;调节血脂,降低血液黏稠度,改善血液流变性;抑制血小板及红细胞聚集,促进纤溶活性;清除氧自由基,对抗脂质过氧化及缺血再灌注损伤等药理作用。笔者对灯盏细辛注射液药理和毒理作用的研究进展进行了综述。
Dengzhanxixin injection is extracted from herbs of Erigeron breviscapusis.Its function includes activate blood,dispel stasis,unblock the collaterals and relieve pain.In clinical,it is widely used for static blood obstruction,wind-stroke and hemiplegia,numbness of limbs,deviated eyes and mouth,dysphasia,chest impediment,heart pain,ischemic stroke,coronary heart disease,and angina pectoris with the pattern mentioned above.In this paper,we planed to review the pharmacological and toxicological effects of Dengzhanxixin injection from relevant studies.

关键词(KeyWords): 灯盏细辛注射液;药理作用;毒理作用
Dengzhanxixin injection;pharmacological effect;toxicological effects

Abstract:

Keywords:

基金项目(Foundation): 国家“重大新药创制”科技重大专项(2009ZX09502-030)“中药上市后评价关键技术研究”

作者(Authors): 郭婷;黎元元;
GUO Ting1,LI Yuan-yuan2(1.Yunnan Biovalley Dengzhanhua Pharmaceutical Co.,Ltd.,Kunming 652300,China; 2.Institute of Basic Research in Clinical Medcine,China Academy of Chinese Medical Sciences,Beijing 100700,China)

参考文献(References):

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