中国中药杂志

2012, v.37(16) 2413-2416

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基于木通皂苷探讨中药质量评价用对照提取物研究
Study on reference extracts for quality assessment on traditional Chinese medicines based on akebiae saponin

袁贤达;高慧敏;王智民;张启伟;
YUAN Xianda 1,2,GAO Huimin 1,2,WANG Zhimin 1,2,ZHANG Qiwei 1,2(1.Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China; 2.National Engineering Laboratory of Quality Control Technology of Chinese Materia Medica,Beijing 100700,China)

摘要(Abstract):

在分析总结中药对照提取物应用现状的基础上,提出中药质量评价用对照提取物根据用途不同,分为3类:①药材或挥发油对照提取物,用于原药材提取物或含原药材的中成药薄层鉴别;②组分对照提取物,用于某类组分鉴别或色谱峰定位;③标示了待测成分含量的对照提取物,可用于样品的定量分析。针对第3类对照提取物,以木通皂苷为例,从制备工艺、成分鉴定和含量分析等方面探讨了其研制思路和方法。
On the basis of analysis and summary of current application of reference extracts of traditional Chinese medicine,reference extracts for quality assessment of traditional Chinese medicines are divided into three classes by purpose:①herbal or volatile oil reference extracts for TLC identification of original herbal medicines or patent traditional Chinese medicines containing original herbal medicines.②component reference extracts for identification of certain components or positioning of chromatographic peaks.③reference extracts marked with component content to be determined for quantitative analysis on samples.For the third kind of reference extracts,akebiae saponin was taken as an example for preparation thought and methods in such aspects as preparation process,component identification and content analysis.

关键词(KeyWords): 木通皂苷;质量评价;对照提取物
akebiae saponin;quality evaluation;reference extract

Abstract:

Keywords:

基金项目(Foundation): 国家“重大新药创制”科技重大专项(2009ZX09301-005,2009ZX09308-003);; 中医药行业科技专项(200707009);; 中药质量控制技术国家工程实验室项目(2010DZHT002)

作者(Author): 袁贤达;高慧敏;王智民;张启伟;
YUAN Xianda 1,2,GAO Huimin 1,2,WANG Zhimin 1,2,ZHANG Qiwei 1,2(1.Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China; 2.National Engineering Laboratory of Quality Control Technology of Chinese Materia Medica,Beijing 100700,China)

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