中国中药杂志

2021, v.46(24) 6343-6352

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滇重楼民族民间应用及传统功效的物质基础研究
Traditional use of Paris polyphylla and its active components

晏秀祥;潘齐冬;孙浩云;高路;杨蓉;杨立新;
YAN Xiu-xiang;PAN Qi-dong;SUN Hao-yun;GAO Lu;YANG Rong;YANG Li-xin;Kunming Institute of Botany, Chinese Academy of Sciences;School of Ethnic Medicine, Yunnan Minzu University;School of Marxism, Southwest Forestry University;

摘要(Abstract):

该文综述了滇重楼植物的民族民间应用情况及其相关传统功效的物质基础,为滇重楼植物开发利用提供参考。研究表明共有8个少数民族使用滇重楼,整理分析62个验方的主治疾病、传统炮制方法、配伍药材和使用剂量,其中单方29个、复方33个。民间验方数量统计结果表明,在8个少数民族中排名前三的分别是彝族(18个)、纳西族(13个)、白族(12个)。滇重楼在民族民间应用广泛,主要用于治疗9类疾病,目前在皮肤类疾病、中毒及损伤类疾病等相关领域已具较好规模。通过对滇重楼的传统功效物质基础整理发现,共有26个化合物与传统功效记载有关,其中有19个甾体皂苷。甾体皂苷是滇重楼植物的主要活性物质,很好地解释了其在传统功效中治疗肿瘤、疔疖肿毒,抗菌、消炎、止血等作用。该文通过对滇重楼传统功效物质基础的初步研究发现,其在抗肿瘤,呼吸系统、消化系统、泌尿生殖系统等疾病上,民族民间传统治疗功效确切,为相关基础研究和制剂研发提供了线索。
This paper reviewed the traditional use of Paris polyphylla and its active components, aiming to provide reference for the development and utilization of this plant. It was found that P. polyphylla has been used as a medicinal plant by eight ethnic minorities. A total of 62 experiential effective recipes, including 29 simple recipes and 33 compound recipes, were analyzed for their indications, traditional processing methods, medicinal compatibilities, and administration doses. The top three in the eight ethnic minorities sorted by the quantity of folk recipes were the Yi nationality(18), Naxi nationality(13) and Bai nationality(12). P. polyphylla has been widely employed for the treatment of nine categories of diseases, especially the dermatologic diseases, trauma, and toxicosis currently. The collating of material basis for its traditional functions revealed 26 active components, among which 19 were steroidal saponins capable of resisting cancer, furuncles, carbuncles, abscesses, bacteria, inflammation and stopping bleeding. This study preliminarily proved the efficacy of P. polyphylla in treating cancer and respiratory system, digestive system, and genitourinary system diseases, which has provided clues for related basic research of P. polyphylla and development of new preparations.

关键词(KeyWords): 滇重楼;民族民间;传统功效;物质基础;甾体皂苷
Paris polyphylla;ethnic and folk;traditional efficacy;active components;steroidal saponins

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金面上项目(31970357)

作者(Author): 晏秀祥;潘齐冬;孙浩云;高路;杨蓉;杨立新;
YAN Xiu-xiang;PAN Qi-dong;SUN Hao-yun;GAO Lu;YANG Rong;YANG Li-xin;Kunming Institute of Botany, Chinese Academy of Sciences;School of Ethnic Medicine, Yunnan Minzu University;School of Marxism, Southwest Forestry University;

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