聂黎行;金红宇;王钢力;田金改;林瑞超;
NIE Li-xing,JIN Hong-yu,WANG Gang-li,TIAN Jin-gai,LIN Rui-chao(National Institute for the Control of Pharmaceutical and Biological Products,Beijing 100050,China)

• 1:中国药品生物制品检定所

摘要(Abstract)：

目的:建立了4种中药注射液中重金属及有害元素的残留量的测定方法。方法:采用石墨炉原子吸收分光光度法测定铅、镉、铜,原子荧光法测定砷、汞。对样品的前处理方法进行了优化。结果:5种重金属元素的回收率在91%~112%,精密度<2%。铅、镉、铜、砷、汞的检出限分别为0.28,0.014,0.49,0.19,0.061μg.L-1。结论:方法简便、灵敏、准确、可靠,值得推广。
Methods for determination of heavy metals and harmful residues in traditional Chinese medicine injection were established.Graphite furnace atomic absorption spectrometry was used for determination of lead,cadmium and copper,atomic fluorescence spectrometry for arsenic and mercury.The preprocessing method was optimized.The average recoveries of 5 elements were between 91% and 112% while the precisions were less than 2%.The determination limit of lead,cadmium,copper,arsenic and mercury were 0.28,0.014,0.49,0.19,0.061 μg·L-1,respectively.The proposed method was simple,sensitive,accurate and reliable,and could be used widely.

关键词(KeyWords)： 重金属及有害元素;中药注射液;原子吸收分光光度法;原子荧光法
heavy metals and harmful elements residues;traditional chinese medicine injection;atomic absorption spectrometry;atomic fluorescence spectrometry

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 聂黎行;金红宇;王钢力;田金改;林瑞超;
NIE Li-xing,JIN Hong-yu,WANG Gang-li,TIAN Jin-gai,LIN Rui-chao(National Institute for the Control of Pharmaceutical and Biological Products,Beijing 100050,China)

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DOI:

参考文献(References)：

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• [4]宗水珍,汪学英,徐娟.石墨炉原子吸收分光光度法测定茵栀黄注射液及其中的铅镉[J].应用化学,2007,24(10):1219.