中国中药杂志

2007, (22) 2413-2415

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

黄芩苷体内抗流感病毒作用
Effect of baicalin on in vivo anti-virus

初正云;初明;滕宇;
CHU Zheng-yun1,CHU Ming2,TENG Yu1(1.Pharmacy department,Liaoning University of Traditional Chinese Medicine,Shenyang 110032,China;2.Department of Immunology,School of Basic Medicine,Beijing University,Beijing 100083,China)

摘要(Abstract):

目的:研究黄芩苷体内抗流感病毒(influenza virus,IV)作用。方法:采用体内实验方法,对小鼠先预防给药(2 d)后感染流感病毒(A/FM/1/47)或先感染流感病毒(1 d)后治疗给药的方法观察黄芩苷的抗流感病毒作用。结果:黄芩苷可明显延长流感病毒感染小鼠的存活时间(P<0.01);对小鼠肺内的流感病毒有一定的清除作用,能降低肺内流感病毒的血凝滴度和感染力;减轻小鼠肺内的炎性病变。结论:黄芩苷具有明显的抗流感病毒作用。
Objective: This study is about the in vivo antivirus effect of baicalin.Method: Adopting in vivo experiment,we administered one group of mice 2 days before infected with influenza virus(A/FM/1/47),while administer the other group with baicalin one day after infected,to observe the effect of baicalin in protecting and curing mice against influenza virus.Result: Baicalin can obviously prolong the survival time of mice infected with influenza virus(A/FM/1/47)(P<0.01),eliminate the influenza virus in lung,reduce the hemagglutination tite and infectivity in pulmo,and reverse mice's pneumonic pathological changes.Conclusion: Baicalin can obviously counteract influenza virus.

关键词(KeyWords): 黄芩苷;流感病毒;肺指数
baicalin;influenza virus;pulmo index

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 初正云;初明;滕宇;
CHU Zheng-yun1,CHU Ming2,TENG Yu1(1.Pharmacy department,Liaoning University of Traditional Chinese Medicine,Shenyang 110032,China;2.Department of Immunology,School of Basic Medicine,Beijing University,Beijing 100083,China)

Email:

DOI:

参考文献(References):

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享