中国中药杂志

2020, v.45(19) 4545-4554

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

论中药“辨状论质”之辨色泽与品质评价的生物学内涵研究
Biological research of color and quality evaluation in "quality discrimination by character" of Chinese medicine

刘天睿;金艳;孟虎彪;赵玉洋;周骏辉;袁媛;黄璐琦;
LIU Tian-rui;JIN Yan;MENG Hu-biao;ZHAO Yu-yang;ZHOU Jun-hui;YUAN Yuan;HUANG Lu-qi;State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences;

摘要(Abstract):

在经验鉴别"辩状论质""五象七原"等理论中,色泽是中药品质评价的重要指标之一。一方面,药材基原植物细胞中的色素是药材色泽形成的根本原因,包括药材表面的色泽特征、内部颜色以及炮制前后的色泽变化,是药材"优形"的一种典型表现;另一方面,大部分色素具有抗氧化、抗肿瘤、抗动脉粥样硬化、预防冠心病、保护心血管、增强免疫力等广泛的药理活性,使得药材的"外在色泽优形"与"内在色素优质"是互为统一的。该文系统综述了"辨色论质"的研究现状,整理了中药色泽L~*,a~*,b~*与生物碱、黄酮、萜类等活性成分相关性研究的进展,旨在为"优色、优质"的定量表征奠定基础;总结了中药主要色素类成分生物合成及其表达调控的研究进展,并分析了影响中药主要色素积累的生物学成因,以期为诠释药材辨状论质之"辩色论质"品质评价的生物学内涵,建立中药材现代化质量控制体系提供参考。
In the theories of empirical identification of "arguments on quality" and "five elephants and seven originals", color is regarded as one of the important indicators in the quality evaluation of Chinese medicine. The color of medicinal material including the surface color, the internal color, and the color after processing is caused by the pigment in the cells, which is a characteristic of the "optimal shape". Most pigments have a wide range of pharmacological activities such as anti-oxidation, anti-tumor, anti-atherosclerosis, prevention of coronary heart disease, protection of cardiovascular function, enhancement of immunity, etc. Therefore, the "optimal color" of medicinal materials is unified with the "high quality". This article systematically reviews the research status of "quality discrimination by color", the correlation between L~*, a~*, b~* color space and active ingredients such as alkaloids, flavonoids, terpenes, etc. to explain the "quality discrimination by color" in quantitative characterization. We also summary the research progress on the biosynthesis and regulation of the main pigment components of traditional Chinese medicine, and analyze the biological causes that affect the accumulation of the main pigments. We aim to provide a reference for the theory "quality discrimination by color" in biological knowledge to establish a modern quality control system for Chinese herbal medicines.

关键词(KeyWords): 中药品质;色泽;生物合成;优形;优质
Chinese medicine quality;color;biosynthesis;optimal character;high quality

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金重大项目(81891013);; 中央本级重大增减支项目(2060302);; 中央级公益性科研院所基本科研业务费专项(ZZ10-008)

作者(Author): 刘天睿;金艳;孟虎彪;赵玉洋;周骏辉;袁媛;黄璐琦;
LIU Tian-rui;JIN Yan;MENG Hu-biao;ZHAO Yu-yang;ZHOU Jun-hui;YUAN Yuan;HUANG Lu-qi;State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences;

Email:

DOI: 10.19540/j.cnki.cjcmm.20200726.102

参考文献(References):

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享