中国中药杂志

2021, v.46(19) 4922-4929

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病证结合药理学:中药药理学研究的策略与方法
Pharmacology of combination of disease and syndrome:strategies and methods of pharmacology of Chinese medicine

任钧国;刘建勋;韦佳慧;
REN Jun-guo;LIU Jian-xun;WEI Jia-hui;Beijing Key Laboratory of Pharmacology of Traditional Chinese Medicine, Institute of Basic Medicine,Xiyuan Hospital, China Academy of Chinese Medical Sciences;

摘要(Abstract):

中药药理学是在中医药理论指导下,运用现代科学技术研究中药与机体(含病原体)相互作用及作用规律的学科,但中药药理学在发展过程中主要以现代医药学的理论、技术和方法作为指导,在一定程度上忽视了中医药理论,其在本质上并不符合中药作用的特点,尚未能建立全面系统的符合中医药特点的研究思路、策略、方法、技术等,进而无法全面揭示中医药防治疾病的科学内涵。为此,该文根据中医药现代发展的趋势,结合中药药理学的研究现状,提出病证结合药理学的概念,并对此概念相关的背景、内容、方法、意义等方面进行了阐述,旨在提高病证结合药理学研究的规范性,更好的指导临床合理安全用药,为中药药理学学科的科学发展提供新的借鉴,促进中药现代化事业的发展。
The pharmacology of Chinese medicine is an academic discipline that studies the interaction between Chinese medicine and organism(including pathogens) by modern science and technology under the guidance of traditional Chinese medicine(TCM) theories. However, the pharmacology of Chinese medicine is mainly guided by the theories, techniques, and methods of modern medicine in the development, and TCM theories have been ignored to a certain extent, which does not conform to the action characteristics of Chinese medicine in essence. Since systematic research ideas, strategies, methods, and technologies that conform to the characteristics of TCM have not been established, it is unable to reveal the scientific connotation of TCM in the prevention and treatment of diseases. Therefore, according to the trend of the modern development of TCM and the research status of pharmacology of Chinese medicine, this study put forward the concept of pharmacology of combination of disease and syndrome and expounded the relevant background, content, methods, and significance of this concept. It is expected to improve the standardization of pharmacology of combination of disease and syndrome, guide the safe medication, provide new references for the scientific development of pharmacology of Chinese medicine, and promote the development of the modernization of Chinese medicine.

关键词(KeyWords): 中药药理;病证结合药理学;病证结合药效学;病证结合药动学;病证结合毒理学
pharmacology of Chinese medicine;pharmacology of combination of disease and syndrome;pharmacodynamics of combination of disease and syndrome;pharmacokinetics of combination of disease and syndrome;toxicology of combination of disease and syndrome

Abstract:

Keywords:

基金项目(Foundation): 国家“重大新药创制”科技重大专项(2017ZX09301018);; 中国中医科学院基本科研业务费自主选题(ZZ11-027)

作者(Author): 任钧国;刘建勋;韦佳慧;
REN Jun-guo;LIU Jian-xun;WEI Jia-hui;Beijing Key Laboratory of Pharmacology of Traditional Chinese Medicine, Institute of Basic Medicine,Xiyuan Hospital, China Academy of Chinese Medical Sciences;

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