麦角甾酮的药理活性、药代动力学及含量测定研究进展Research progress on pharmacology,pharmacokinetics and determination of ergosta-4,6,8( 14),22-tetraen-3-one
陈晗;陈丹倩;李全福;李鹏飞;陈华;赵英永;
摘要(Abstract):
麦角甾酮是多种药用真菌的主要化学成分之一,具有利尿、抗肿瘤、免疫抑制、治疗慢性肾脏病等多种生物活性。基于已报道的相关文献,该文综述了麦角甾酮的波谱特征、含量测定、药理活性及药代动力学等研究进展,为深入研究与开发利用麦角甾酮提供一定价值的参考。
关键词(KeyWords): 麦角甾酮;利尿;慢性肾脏病;细胞毒活性;药代动力学;含量测定
基金项目(Foundation): 教育部“新世纪优秀人才计划”项目(NCET-13-0954);; 长江学者和创新团队发展计划(IRT1174);; 国家自然科学基金项目(J1210063,81202909,81274025);; 陕西省国际合作项目(2013KW31-01);; 国家创新训练计划项目(201310697004)
作者(Author): 陈晗;陈丹倩;李全福;李鹏飞;陈华;赵英永;
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