中国中药杂志

2009, v.34(10) 1220-1222

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黄花乌头茎叶化学成分的研究
Studies on chemical constituents from leaves and stems of Aconitum coreanum

李岩;梁帅;
LI Yan1,LIANG Shuai2 (1.Jilin Province Brain Hospital,Siping 136000,China;2.Siping Institute of Food and Drug Control,Siping 136000,China)

摘要(Abstract):

目的:对毛茛科植物黄花乌头Aconitum coreanum的茎叶进行化学成分研究。方法:黄花乌头茎叶的醇提物用各种柱色谱分离和纯化,根据化合物的理化性质和波谱学数据鉴定其结构。结果:分离得到5个化合物,关附壬素(1),关附未素(2),β-谷甾醇(3),D-甘露醇(4),胡萝卜苷(5)。结论:化合物2为新化合物,其余化合物皆为首次从黄花乌头茎叶中获得。
Objective:To study the chemical constituents in the leaves and stems of Aconitum coreanum.Method: The isolation and purification of chemical constituents were carried out on silica gel and polyamide column chromatographic.Their structures were identified by physico-chemical properties and spectral analysis.Result: Five compounds were obtained and their structures were identified as guan-fu base I(1),guan-fu base R(2),β-sitosterol(3),D-mannitol(4),daucosterol(5).Conclusion: Compound 2 is a new compound.Compounds 1 and 3,4 are isolated from the leaves and stems of A.coreanum for the first time.

关键词(KeyWords): 黄花乌头;化学成分;关附未素
Aconitum coreanum;chemical constituents;guan-fu base R

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作者(Author): 李岩;梁帅;
LI Yan1,LIANG Shuai2 (1.Jilin Province Brain Hospital,Siping 136000,China;2.Siping Institute of Food and Drug Control,Siping 136000,China)

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