中国中药杂志

2014, v.39(19) 3788-3793

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

绵枣儿中高异黄酮和二苯乙烯类化合物
Homoisoflavanones and stilbenes from fresh bulb of Scilla scilloides

王延敏;樊孟洋;李娟;王智民;高慧敏;
WANG Yan-min;FAN Meng-yang;LI Juan;WANG Zhi-min;GAO Hui-min;Institute of Chinese Materia Medica,China Academy of Chinese Medical sciences;National Engineering Laboratory for Quality Control Technology of Chinese herbal Medicines;He'nan University of Traditional Chinese Medicine;Xinyang Agricultural College;

摘要(Abstract):

绵枣儿来源于风信子科植物绵枣儿Scilla scilloides(Lindl.)Druce的鳞茎。本研究采用HPD100大孔树脂、硅胶、Sephadex LH-20、ODS柱色谱和半制备HPLC等方法,从采自河南信阳的绵枣儿中分离出17个化合物;根据化合物的理化性质和波谱数据,分别鉴定为2-羟基-7-甲氧基绵枣儿素(1),绵枣儿素(2),5,7-dihydroxy-3',4'-dimethoxyspiro{2H-1-benzopyran-7'-bicyclo[4.2.0]octa[1,3,5]-trien}-4-one(3),socialinone(4),4-甲基白藜芦醇(5),(E)-白藜芦醇(6),scillavone A(7),3,9-dihydroeucomnalin(8),3-(3-羟基-4-甲氧基苄基)-5,7-二羟基苯并二氢吡喃-4-酮(9),(3R)-5,7,3'-trihydroxy-4'-methoxyspiro{2H-1-benzopyran-7'-bicyclo[4,2,0]octa[1,3,5]-trien}-4-one(10),scillabene A(11),2-羟基绵枣儿素(12),3-(4-羟基苄基)-5,7-二羟基苯并二氢吡喃-4-酮(13),3-(4-羟基亚苄基)-5,7-二羟基苯并二氢吡喃-4-酮(14),3-(4-羟基苄基)-5-羟基-7,8-二甲氧基苯并二氢吡喃-4-酮(15),3-(4-羟基苄基)-5-羟基-6,7-二甲氧基苯并二氢吡喃-4-酮(16),3-(4-羟基苄基)-5,8-二羟基-7-甲氧基苯并二氢吡喃-4-酮(17),其中化合物3,4,6,9,13和15~17为首次从绵枣儿植物中分离得到。
Mian-Zao-Er was collected from the bulbs of Scilla scilloides( Lindl.) Druce,belonging to the Hyacinthaceae family. 17 compounds were obtained using various column chromatographies on macroporus resin( HPD100),silica gel,Sephadex LH-20 and ODS,as well as semi-preparative HPLC. Their structures were elucidated on the basis of physicochemical properties and spectral data as 2-hydroxy-7-methoxyscillascillin( 1),scillascillin( 2),5,7-dihydroxy-3',4'-dimethoxyspiro{ 2H-1-benzopyran-7'-bicyclo[4.2. 0]octa [1,3,5]-trien}-4-one( 3),socialinone( 4),4-methylresveratrol( 5),( E)-resveratrol( 6),scillavone A( 7),3,9-dihydroeucomnalin( 8),3-( 3-hydroxy-4-methoxybenzyl)-5,7-dihydroxychroman-4-one( 9),( 3R)-5,7,3'-trihydroxy-4'-methoxyspiro{ 2H-1-benzopyran-7'-bicyclo[4,2,0]octa[1,3,5]-trien}-4-one( 10),scillabene A( 11),2-hydroxyscillascillin( 12),3-( 4-hydroxybenzyl)-5,7-dihydroxychroman-4-one( 13),3-( 4-hydroxybenzylidene)-5,7-dihydroxychroman-4-one( 14),3-( 4-hydroxybenzyl)-5-hydroxy-7,8-dimethoxychroman-4-one( 15),3-( 4-hydroxybenzyl)-5-hydroxy-6,7-dimethoxychroman-4-one( 16),and3-( 4-hydroxybenzyl)-5,8-hydroxy-7-methoxychroman-4-one( 17). Among them,compounds 3,4,6,9,13 and 15-17 were isolated from this plant for the first time.

关键词(KeyWords): 绵枣儿;高异黄酮;二苯乙烯
Scilla scilloides;homoisoflavanone;stilbene

Abstract:

Keywords:

基金项目(Foundation): 中央级公益性科研院所基本科研业务费专项(ZZ070820)

作者(Author): 王延敏;樊孟洋;李娟;王智民;高慧敏;
WANG Yan-min;FAN Meng-yang;LI Juan;WANG Zhi-min;GAO Hui-min;Institute of Chinese Materia Medica,China Academy of Chinese Medical sciences;National Engineering Laboratory for Quality Control Technology of Chinese herbal Medicines;He'nan University of Traditional Chinese Medicine;Xinyang Agricultural College;

Email:

DOI:

参考文献(References):

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享