黄火强;闫美娜;朴香兰;
HUANG Huoqiang,YAN Meina,PIAO Xianglan(Key Lab of Chinese Minority Traditional Medicine,Ministry of Education,Academe of Chinese Minority Traditional Medicine, Minzu University of China,Beijing 100081,China)

• 1:中央民族大学中国数民族传统医学研究院中国少数民族传统医学教育部重点实验室

摘要(Abstract)：

目的:研究菊科药用植物三角叶凤毛菊Saussurea deltoidea的化学成分。方法:利用正/反相硅胶柱层析色谱、凝胶分子筛色谱、HPLC等色谱方法进行化合物的分离,利用波谱学方法鉴定化合物结构。结果:从三角叶凤毛菊中分离出10个化合物,其结构分别鉴定为(3R,6R,7E)-3-hydroxy-4,7-megastigmadien-9-one(1),(3S,5R,6S,7E)-5,6-epoxy-3-hydroxy-7-me-gastigmen-9-one(2),3-hydroxy-β-damascone(3),S-(+)-dehydrovomifoliol(4),megastigman-5-ene-3β,9R-diol(5),coniferaldehyde(6),β-hydroxypropiovanillone(7),3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-1-propanone(8),dihydrosyringenin(9),4-[(1S)-3-hydroxy-1-methoxypropyl]-2,6-dimenthoxyphenol(10)。结论:化合物1～10均是首次从该植物中分离得到。
To investigate the chemical constituents of Saussurea deltoidea,10 compounds were isolated from the title plant by various chromatography methods such as silica gel,RP-18 silica gel,Sephadex LH-20 column chromatography,HPLC,et al.Their structures were elucidated by spectral analysis.Five isoprenoids and Five phenylpropanoids were isolated and elucidated as(3R,6R,7E)-3-hydroxy-4,7-megastigmadien-9-one(1),(3S,5R,6S,7E)-5,6-epoxy-3-hydroxy-7-megastigmen-9-one(2),3-hydroxy-β-damascone(3),S-(+)-dehydrovomifoliol(4),megastigman-5-ene-3β,9R-diol(5),coniferaldehyde(6),β-hydroxypropiovanillone(7),3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-1-propanone(8),dihydrosyringenin(9),4-[(1S)-3-hydroxy-1-methoxypropyl]-2,6-dimenthoxyphenol(10).All the compounds were isolated from S.deltoidea for the first time.

关键词(KeyWords)： 三角叶凤毛菊;化学成分;类异戊二烯;苯丙素
Saussurea deltoidea;chemical constituents;isoprenoid;phenylpropanoid

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(30973960/H2818)

作者(Authors): 黄火强;闫美娜;朴香兰;
HUANG Huoqiang,YAN Meina,PIAO Xianglan(Key Lab of Chinese Minority Traditional Medicine,Ministry of Education,Academe of Chinese Minority Traditional Medicine, Minzu University of China,Beijing 100081,China)

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