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粉防己碱对血小板聚集、粘附及血凝的影响
Effects of Tetrandrine on Platelet Aggregation, Platelet Adhesion and Coagulation

吴树勋,赵振军,齐晖
Wu Shuxun, Zhao Zhenjun Qi Hui (Hebei Academy of Medical Sciences, Shijiazhuang 050021)

摘要(Abstract):

在体外实验中观测到粉防己碱可明显抑制ADP和胶原诱导的大鼠血小板聚集反应。对血小板粘附、血栓形成有明显抑制作用,而对凝血酶凝血时间、血浆凝固时间无明显影响。
We examined the effect of tetrandrine on platelet aggregation, platelet adhesion and coagulation in vitro. The results showed that tetrandrine markedly inhibited the platelet aggregation induced by ADP or collagen. Tetrandrine also markedly inhibited platelet adhesion and thrombosis, but didn't change thrombin coagulation time and plasma coagulation time obviously.

关键词(KeyWords): 粉防已碱(tetrandrine);血小析聚集;凝血酶凝血时间;血浆凝固时间;血栓形成
tetrandrine; platelet aggregation; thrombin coagulation time; plasma coagulation time; thrombosis

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作者(Author): 吴树勋,赵振军,齐晖
Wu Shuxun, Zhao Zhenjun Qi Hui (Hebei Academy of Medical Sciences, Shijiazhuang 050021)

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