中国中药杂志

2010, v.35(16) 2119-2123

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丹参中丹参酮Ⅱ_A含量的数据分布特征与差异原因分析
Data distribution characteristics and deviation of tanshinoneⅡ_A content in Radix Salviae Miltiorrhizae

马云桐;陈新;陈静;何忠宝;王菁;严铸云;万德光;
MA Yuntong,CHEN Xin,CHEN Jing,HE Zhongbao,WANG Jing,YAN Zhuyun,WAN Deguang (College of Pharmacy,Chengdu University of Traditional Chinese Medicine,Key Laboratory of Standardization of Chinese Herbal Medicines of Ministry of Education,Chengdu 610075,China)

摘要(Abstract):

目的:探索丹参中丹参酮ⅡA的含量变化规律,寻找不同研究结果存在差异的原因。方法:结合本课题组的研究结果,并收集了1997年以来不同产地丹参酮ⅡA的含量测定数据,进行探索性数据分析和描述性统计分析。结果和结论:丹参野生药材中丹参酮ⅡA含量普遍高于栽培品,近50%栽培品丹参酮ⅡA低于0.2%;数据的统计模式存在较大的差异,引起数据差异较大,其中以四川产地的数据分歧最大;野生丹参的变异系数低于栽培品,不同产地栽培丹参的变异系数不同,反映出质量的均一性和稳定性不同;市购样品的变异系数大于自采样品;加热回流提取法得到丹参酮ⅡA结果偏低。
Objective: To analyze the content of tanshinoneⅡA in Radix Salviae Miltiorrhizae from different habitats are regularly altered and find out the deviation between the studies.Method: The data of the content of tanshinone ⅡA in samples of Radix Salviae Miltiorrhizae from different areas and related information since 1997 was collected and statistically analyzed.Result and Conclusion: The content of tanshinoneⅡA in wild Salvia was generally higher than that in the cultivated Salvia,and the content in nearly half cultivated Salvia was less than 0.2%.There existed a big difference between the used statistical model,and the data related the content in samples from Sichuan was the most divisive.The coefficient of variation of wild Salvia was below the cultivated Salvia,and the cultivated Salvia from different areas showed different coefficients of variation.The content of tanshinoneⅡA was lower when samples were extracted using the heating reflux method.

关键词(KeyWords): 丹参;丹参酮ⅡA;产地;统计分析
Radix Salviae Miltiorrhizae;content of tanshinone ⅡA;habitats;statistical analysis

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基金项目(Foundation): 国家“十一五”科技支撑计划项目(2006BAI09B03-4)

作者(Author): 马云桐;陈新;陈静;何忠宝;王菁;严铸云;万德光;
MA Yuntong,CHEN Xin,CHEN Jing,HE Zhongbao,WANG Jing,YAN Zhuyun,WAN Deguang (College of Pharmacy,Chengdu University of Traditional Chinese Medicine,Key Laboratory of Standardization of Chinese Herbal Medicines of Ministry of Education,Chengdu 610075,China)

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