中国中药杂志

1995, (04)

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黄芪总黄酮对羟自由基所致哺乳动物细胞损伤的防护作用
Protective Effect of Total Flavonoids of Radix Astragali on Mammal ian Cell Damage Caused by Hydroxyl Radical

汪德清,沈文梅,田亚平,董振南,刘国廉,孙仲怡,杨素霞,周淑珍
Wang Deqing;Shen Wenmei Tian Yaping and Dong Zhennan(Department of Biochemistry,General Hhospital of PLA,Beijing 100853)

摘要(Abstract):

黄芪总黄酮对羟自由基所致V79细胞的多种损伤皆有不同程度的防护作用。可降低细胞脂质过氧化物的生成,升高细胞SOD活性,维持细胞正常代谢。
iu Guolian; Sun Zhongyi; Yang Suxia and Zhou Shuzhen(Institute of Radiation Medicine,Academy of Military Medical Sciences,Beijing 100850)The protective effect of total flavonoids of Radix Astragali (TFA)on V_(79) cell damage caused by H_2O_2-Fe ̄(2+) sys-tem has been studied. The results show that total flavonoids of Radix Astragali inhibit lipid peroxides and increase SODactivity. It has also been found that TFA has different protective effect against various damages of V_(79) cells caused byhydroxyl radical.

关键词(KeyWords): 黄芪总黄酮,羟自由基,V79细胞
TFA; hydroxyl radical;V_(79) cells

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作者(Author): 汪德清,沈文梅,田亚平,董振南,刘国廉,孙仲怡,杨素霞,周淑珍
Wang Deqing;Shen Wenmei Tian Yaping and Dong Zhennan(Department of Biochemistry,General Hhospital of PLA,Beijing 100853)

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