紫堇属藏药的化学与药理学研究进展
投稿时间:2013-12-23    责任编辑:  点此下载全文
引用本文:尚伟庆,陈月梅,高小力,普尺,屠鹏飞,柴兴云.紫堇属藏药的化学与药理学研究进展[J].中国中药杂志,2014,39(7):1190.
DOI:10.4268/cjcmm20140709
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作者中文名作者英文名单位中文名单位英文名E-Mail
尚伟庆 SHANG Wei-qing 缙云县中医院, 浙江 缙云 321400 Jinyun Hospital of Traditional Chinese Medicine, Jinyun 321400, China  
陈月梅 CHEN Yue-mei 北京中医药大学 中药现代研究中心, 北京 100029 Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China  
高小力 GAO Xiao-li 北京中医药大学 中药现代研究中心, 北京 100029 Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China  
普尺 PU-Chi 西藏自治区藏药审评认证中心, 西藏 拉萨 850000 Review of the Tibet Autonomous Region Medicine Certification Center, Lasa 850000, China  
屠鹏飞 TU Peng-fei 北京中医药大学 中药现代研究中心, 北京 100029 Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China  
柴兴云 CHAI Xing-yun 北京中医药大学 中药现代研究中心, 北京 100029 Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China xingyunchai@yeah.net 
基金项目:国家自然科学基金项目(81303309);教育部留学回国人员科研启动基金项目(2013-07)
中文摘要:我国有紫堇属植物约298种,其中特有10组219种,广泛用于藏医藏药。紫堇属藏药主要用于感冒发烧、肝炎、水肿、胃炎、胆囊炎、高血压等多种疾病。其化学成分主要为异喹啉生物碱。现代药理学研究表明紫堇属植物对心血管系统、中枢神经系统、抗菌、镇痛、抗炎、保肝、抗氧化等,皆有明显的作用。该文对我国紫堇属藏药的种属、分布、化学成分、药理活性等进行系统综述,并对其相关研究现状和前景进行了展望,以期为紫堇属藏药的深入研究和开发利用提供参考。
中文关键词:罂粟科  紫堇属  藏药  化学成分  药理作用  综述
 
Phytochemical and pharmacological advance on Tibetan medicinal plants of Corydalis
Abstract:It was estimated that about 428 species of genus Corydalis are distributed all worldwide, with about 298, especially 10 groups and 219 species being uniquely spread in China. The genus Corydalis have been widely employed as folk medicines in China, especially as traditional Tibetan medicines, for treatment of fever, hepatitis, edema, gastritis, cholecystitis, hypertension and other diseases. The phytochemical studies revealed that isoquinoline alkaloids are its major bioactive ingredients. The extensive biological researches suggested its pharmacological activities and clinic applications against cardiovascular diseases and central nervous system, antibacterial activities, analgesic effects, anti-inflammatory, anti-oxidation and anti-injury for hepatocyte, and so on. As an effort in promoting the research of pharmacodynamic ingredients, this article presents an overview focusing on the distribution, phytochemical and pharmacological results of Corydalis species that have been applied in traditional Tibetan medicinal, hopefully to provide a reference for the new Tibetan medicine development from Corydalis plant resource.
keywords:Papaveraceae  Corydalis  Tibetan medicine  chemical constituents  pharmacological activities  review
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