Development of α-glucosidase inhibitor from medicinal herbs
Received: July 09, 2009  
DOI:10.4268/cjcmm20101229
KeyWord:α-glucosidase inhibitor  medicinal herbs  screening model  evaluation of mechanism
AuthorInstitutionE-mail
JI Fang School of Pharmacy, Lanzhou University, Lanzhou 730000, China  
XIAO Guochun Medicine School of Gansu Province, Lanzhou 730000, China  
DONG Li School of Pharmacy, Lanzhou University, Lanzhou 730000, China  
MA Zijiao School of Pharmacy, Lanzhou University, Lanzhou 730000, China  
NI Jingman School of Pharmacy, Lanzhou University, Lanzhou 730000, China lynjm2004@hotmail.com 
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Abstract:
      α-glucosidase inhibitor can reduce the postprandial hyperglycemia and have good effect on preventing and treating the diabetes and diabetic complication. Along with the application of acarbose which is a kind of α-glucosidase inhibitor, many research groups pay attention to the crude α-glucosidase inhibitor screened from the medicinal herbs in order to find new, safe, and effective medicine. The development of α-glucosidase inhibitor screened from the medicinal herbs and its evaluation in vivo and vitro as well as the varieties of the medicinal herbs that contain α-glucosidase inhibitor in recent 30 years were summarized in this paper.
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