Phytochemical and pharmacological advance on Tibetan medicinal plants of Corydalis
Received:December 23, 2013  
DOI:10.4268/cjcmm20140709
KeyWord:Papaveraceae  Corydalis  Tibetan medicine  chemical constituents  pharmacological activities  review
Author NameAffiliationE-mail
SHANG Wei-qing Jinyun Hospital of Traditional Chinese Medicine, Jinyun 321400, China  
CHEN Yue-mei Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China  
GAO Xiao-li Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China  
PU-Chi Review of the Tibet Autonomous Region Medicine Certification Center, Lasa 850000, China  
TU Peng-fei Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China  
CHAI Xing-yun Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China xingyunchai@yeah.net 
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Abstract:
      It was estimated that about 428 species of genus Corydalis are distributed all worldwide, with about 298, especially 10 groups and 219 species being uniquely spread in China. The genus Corydalis have been widely employed as folk medicines in China, especially as traditional Tibetan medicines, for treatment of fever, hepatitis, edema, gastritis, cholecystitis, hypertension and other diseases. The phytochemical studies revealed that isoquinoline alkaloids are its major bioactive ingredients. The extensive biological researches suggested its pharmacological activities and clinic applications against cardiovascular diseases and central nervous system, antibacterial activities, analgesic effects, anti-inflammatory, anti-oxidation and anti-injury for hepatocyte, and so on. As an effort in promoting the research of pharmacodynamic ingredients, this article presents an overview focusing on the distribution, phytochemical and pharmacological results of Corydalis species that have been applied in traditional Tibetan medicinal, hopefully to provide a reference for the new Tibetan medicine development from Corydalis plant resource.
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